Results 41 to 50 of about 266,854 (316)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Understanding support systems for Parkinson's disease management in community settings: A cross‐national qualitative study

open access: yesHealth Expectations, 2023
Background Health and social care systems face difficulties in managing multimorbidity, disease burden and complex needs in long‐term conditions such as Parkinson's disease. Objective This study aimed to develop a European understanding of how health and
Dia Soilemezi   +10 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

A multi-phase study of contemporary policy and practice in determining nursing skill mix in acute hospitals in Ireland. [PDF]

open access: yes, 2012
The profession of nursing has undergone significant changes in Ireland in the last decade, within the wider health service reform context. Determining the optimal nursing skill mix for acute hospitals is perceived as important to ensure the efficient use
Shannon, Michael
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

An overview of risk prediction models and the implications for nursing practice

open access: yes, 2012
Chronic heart failure is a common and costly condition and is one of the most common causes of hospitalisation and emergency department presentations in the elderly.
Betihavas, Vasiliki (R15061)   +2 more
core   +1 more source

Experiences of Nursing Instructors Related to Safety Issues Using Students as Practice Models in Laboratories: A Focus Group Study

open access: yes, 2022
Aim: Nursing school students perform invasive (i.e., injection, venipuncture) and/or non-invasive procedures (i.e., giving a bed bath and back massage) on each other to master these skills, and nursing instructors reported related safety issues.
Soohyun Park   +5 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Critical analysis of the scientific production on Jean Watson’s Theory of Human Care [PDF]

open access: yesRevista Brasileira de Enfermagem
Objectives: to analyze current scientific production on the use of the theoretical-methodological precepts of Jean Watson’s Theory of Human Care/Clinical Caritas Process. Methods: quantitative, exploratory, descriptive study using data from 1979 to 2023
Shirley da Rocha Afonso   +4 more
doaj   +1 more source

Development of Detailed Clinical Models for Nursing Assessments and Nursing Interventions [PDF]

open access: yesHealthcare Informatics Research, 2011
ObjectivesThe aim of this study was to develop and validate Detailed Clinical Models (DCMs) for nursing assessments and interventions.MethodsFirst, we identified the nursing assessment and nursing intervention entities.
Hyeoun-Ae Park   +4 more
doaj   +1 more source

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