Results 251 to 260 of about 11,697,554 (295)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

AI Cautionary Guide: Pitfalls and Strategies for the Use of Machine Learning in Medical Research. [PDF]

Clin Pharmacol Ther
Liu Q, Huang R, Zhang H, Osborne TF.
europepmc   +1 more source

Statistical mechanics models for multivalent binding

, 2016
Liese, Susanne
core  

Digital Phenotyping in Health Research: Scoping Review of Methods, Gaps, and Opportunities. [PDF]

J Med Internet Res
Badier N, Lafitte A, Difernand A, Aguayo GA, Fagherazzi G, Onnela JP, Vittrant B, Lechat B, De Larochelambert Q, Toussaint JF, Delrieu L.   +10 more
europepmc   +1 more source

Advances in small area population estimation in the absence of national census data. [PDF]

Proc Natl Acad Sci U S A
Tatem AJ, Boo G, Chamberlain HR, Nnanatu CC, Darin E, Leasure DR, Yankey O, Gadiaga A, Juran S, Rodriguez LR, Espey J, Lázár AN.   +11 more
europepmc   +1 more source

Prediction of solubility of hydrogen in chemicals using QSPR-based machine learning approach: a comparative study. [PDF]

J Comput Aided Mol Des
Ebrahimpoor Gorji A, Alopaeus V.
europepmc   +1 more source

Prediction model for compressive strength of alkali-activated multi-source solid-waste grouting materials based on generative adversarial networks and machine learning. [PDF]

PLoS One
Yue Q, Yu G, Yao Y, Yang Z, Li Y, Bai L, Xiong G.   +6 more
europepmc   +1 more source

Generation of dual mouse models of retinal degeneration with slow and rapid progression driven by ectopic RIP3 expression. [PDF]

PLoS One
Do Song Y, Kim J, Jang JH, Kim Y, Oh HK, Ji MJ, Choi M, Park M, Kim DW.   +8 more
europepmc   +1 more source