Clinical significance of stratifying prostate cancer patients through specific circulating genes
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian+12 more
wiley +1 more source
A comparison of methods for analysing compositional data with fixed and variable totals: a simulation study using the examples of time-use and dietary data. [PDF]
Tomova GD+4 more
europepmc +1 more source
Errata: Electronic Interaction in the Free-Electron Network Model for Conjugated Systems. I. Theory [PDF]
Norman S. Ham, Klaus Ruedenberg
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MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Assessing dengue forecasting methods: a comparative study of statistical models and machine learning techniques in Rio de Janeiro, Brazil. [PDF]
Chen X, Moraga P.
europepmc +1 more source
THE ACTIVE AREA IN COURSE OF EXCITATION CONDUCTION (OBSERVATIONS ON LILLIE'S NERVE MODEL)
Kazumi Yamagiwa
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The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
Risk prediction models for non-suicidal self-injurious behavior in patient with depressive disorder: a protocol for systematic review and mata-analyisis. [PDF]
Huang L, Liu X, Xu J, Wang L, Zhang Q.
europepmc +1 more source
Matrix Elements of β-Decay for a Spheroidal Core Model [PDF]
Morikazu Nomoto
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NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source