Results 71 to 80 of about 290,943 (347)

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Effectiveness of the Roy adaptation model-based nursing intervention in improving physiological, psychological, and social outcomes in patients with Parkinson’s disease

BMC Neurology
Objective This study aimed to evaluate the effectiveness of a comprehensive nursing intervention based on Roy’s Adaptation Model (RAM) in improving quality of life, psychological adaptation, and social functioning in patients with Parkinson’s disease (PD)
Le Chen
doaj   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

Impact of Patient Safety Culture on Missed Nursing Care and Adverse Patient Events

Journal of Nursing Care Quality, 2019
Supplemental Digital Content is Available in the Text. Background: A strong patient safety culture (PSC) may be associated with improved patient outcomes in hospitals.
A. Hessels, Manisha Paliwal, S. Weaver, Deeba Siddiqui, T. Wurmser   +4 more
semanticscholar   +1 more source

An Injectable BMP‐2‐Releasing Porous Hydrogel Regulating the Paracrine Effects of ADSCs Promotes Tendon‐to‐Bone Healing in Rotator Cuff Repair

Advanced Science, EarlyView.
This study designs an injectable porous hydrogel (HMs/MBs/ADSCs) integrating hollow microspheres for sustained BMP‐2 release to enhance adipose‐derived stem cells' paracrine effect. It accelerates tendon‐bone healing in rat rotator cuff injuries via spatiotemporal regulation: early AMPK‐mediated mitochondrial protection and late TGF‐β/Smad2/3‐driven ...
Meijuan Yuan, Xiaomei Dai, Yuxia Yang, Shuai Liu, Ziyi Xu, Liang Wang, Junli Shi, Wenkang Liu, Jian Yang, Dianwei Liu, Hang Yao, Wenyong Fei   +11 more
wiley   +1 more source

Nursing Home Status Adjustment for Standardized Mortality and Hospitalization in Dialysis Facility ReportsPlain-Language Summary

Kidney Medicine, 2023
Rationale & Objective: Compared to the original nursing home status (any nursing home stay in the previous calendar year), new nursing home status variables were developed to improve the risk adjustment of Standardized Mortality/Hospitalization Ratio
Shu Chen, Megan Slowey, Valarie B. Ashby, Lonnie Barnes, Aaron Pearson, Jian Kang, Joseph M. Messana   +6 more
doaj  

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Personal Health Tracking: A Paradigm Shift in the Self-Care Models in Nursing. [PDF]

JMIR Nurs, 2023
Choi S.
europepmc   +1 more source

Multifunctional Infrared Polarizer Based on Aligned Growth of High‐Density Boron Nitride Nanotubes

Advanced Science, EarlyView.
This paper presents a novel method for the high‐density, aligned growth synthesis and purification of boron nitride nanotubes (BNNTs). The polarization sensitivity and linear dichroism characteristics of BNNTs in the near‐infrared and mid‐infrared bands are comprehensively verified.
Ningqiang Shi, Xiaofei Xiao, Mingyu Zhang, Zhijun Li, Chuncheng Ban, Jinchang Meng, Nannan Shi, Mingyang Wu, Zebo Zheng, Ling Li   +9 more
wiley   +1 more source

Pedagogical strategies for teaching nursing theories in undergraduate students: A scoping review protocol.

PLoS ONE
From a pedagogical point of view, there is a great deal of creativity and practice in teaching conceptual models and nursing theories. However, there seems to be no synthesis of knowledge regarding the pedagogical methods used to teach them.
Aurélie Demagny-Warmoes, Paul Quindroit, Sébastien Colson   +2 more
doaj   +1 more source