Results 81 to 90 of about 2,479,631 (293)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Moderate deviations and central limit theorem for positive diffusions
Journal of Inequalities and Applications, 2016 In this paper, we establish a central limit theorem and a moderate deviation principle for the positive diffusions, including the CEV and CIR models. The proof is based on the exponential approximations theorem and Burkholder-Davis-Gundy’s inequality.
Yumeng Li, Shuguang Zhang
doaj +1 more source
Large Deviations, Moderate Deviations and LIL for Empirical Processes
The Annals of Probability, 1994 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Acta Scientiarum. Agronomy, 2011 The coefficient of variation (CV) has been the most important statistic to determine the precision of experimental errors, but an even classification for guiding popcorn breeders is still lacking for popping expansion.
Emmanuel Arnhold, Klayton Flávio Milani
doaj +1 more source
Moderate deviations for queues in critical loading
Queueing Systems, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +4 more sources
Moderate Deviations for the Determinant of Wigner Matrices [PDF]
, 2013 We establish a moderate deviations principle (MDP) for the log-determinant $\log | \det (M_n) |$ of a Wigner matrix $M_n$ matching four moments with either the GUE or GOE ensemble. Further we establish Cramér--type moderate deviations and Berry-Esseen bounds for the log-determinant for the GUE and GOE ensembles as well as for non-symmetric and non ...
Döring, Hanna, Eichelsbacher, Peter
openaire +2 more sources
Limiting Distribution of the Score Statistic under Moderate Deviation from a Unit Root in MA(1) [PDF]
This paper derives the asymptotic distribution of Tanaka's score statistic under moderate deviation from a unit root in a moving average model of order one or MA(1).
Ryota Yabe
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source