Results 111 to 120 of about 509,373 (313)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Effect of Blue Finance and Marine Environmental Quality on the Marine Fishery Economy
FishesThis study investigates the effects of blue finance and marine environmental quality of the marine fishery economy using panel data for marine fisheries in China’s coastal provinces spanning 2011–2023.
Yiying Jiang +4 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Journal of Data and Information Science, 2017 This study investigates how online user intention in searching health information is affected by problematic situations.
Xia Lidan, Deng Shengli, Liu Yirong
doaj +1 more source
Stimulant drug effects on attention deficit/hyperactivity disorder: a review of the effects of age and sex of patients [PDF]
, 2010 Objective: As dopamine functioning varies by sex and age it might be expected that the effects of methylphenidate or amfetamine, the psychostimulants used for the treatment of Attention Deficit /Hyperactivity Disorder (ADHD), will also be moderated by ...
Barke, Edmund +2 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Frontiers in Marine ScienceIntroductionMarine petroleum pollution has adversely affected marine ecosystems and human living environments, while improvements in shipping efficiency offer a new avenue for mitigating such pollution.MethodsBased on panel data from 11 coastal regions ...
Xina Ji +4 more
doaj +1 more source
More Than Memories? Schema Transference from Media Characters to Real People [PDF]
, 2011 This study focused on whether personality traits and evaluations of television personalities are used to make inferences about new Social interaction partners. It tested the hypothesis that priming schemas of television personalities will bias inferences
Ray, Hilary
core +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source