Results 141 to 150 of about 509,373 (313)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Moderating effect of the type of brand on the belief-attitude-behaviour model [PDF]
Drawing from the Signaling theory we built a model of the moderating effects of the type of brand in a belief-attitude-behaviour model, namely brand evaluation, brand attitude and purchase intention.
Llonch Andreu, Joan +3 more
core
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
PENGARUH VARIABEL-VARIABEL MONETER TERHADAP KINERJA PERBANKAN ISLAM : UKURAN PERUSAHAAN SEBAGAI VARIABEL MODERAT [PDF]
The growth and competition of Islamic banking in Indonesia is faster and tight, because of that the Islamic banks need to improve its performance in order to attract investors and clients, meanwhile monetary variables influencing on performance of ...
Martokromo, Sriyono Djemain
core
The Moderating Effect of Instant Runoff Voting
Instant runoff voting (IRV) has recently gained popularity as an alternative to plurality voting for political elections, with advocates claiming a range of advantages, including that it produces more moderate winners than plurality and could thus help address polarization.
Kiran Tomlinson +2 more
openaire +2 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Childhood obesity and educational attainment : A systematic review [PDF]
Background This report describes the findings and methods of a systematic review of research which explores the relationship between obesity and educational attainment.
Caird, Jenny +6 more
core +1 more source
Research Note: Treatment effect moderators
Mark J Hancock, Peter Kent
openaire +2 more sources

