Results 61 to 70 of about 241,852 (360)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

INTEGRATION OF RELIGIOUS MODERATION IN ISLAMIC EDUCATION: CHALLENGES AND OPPORTUNITIES IN THE DIGITAL ERA

open access: yesEdukasi Islami: Jurnal Pendidikan Islam
Background: In the face of increasing radicalism and intolerance, Islamic education in Indonesia plays a crucial role in fostering religious moderation.
Abdullah Hanif   +2 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Methods in causal inference. Part 2: Interaction, mediation, and time-varying treatments

open access: yesEvolutionary Human Sciences
The analysis of ‘moderation’, ‘interaction’, ‘mediation’ and ‘longitudinal growth’ is widespread in the human sciences, yet subject to confusion. To clarify these concepts, it is essential to state causal estimands, which requires the specification of ...
Joseph A. Bulbulia
doaj   +1 more source

Gastrin and the Moderate Hypergastrinemias [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
The antral hormone gastrin potently regulates gastric acid secretion and fundic mucosal growth. Consequently, appropriate gastrin secretion and plasma concentrations are important for the early phases of digestion. This review describes as the first premise the normal biogenesis of gastrin in the antral mucosa, but also mentions the extraantral ...
openaire   +4 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

LLM-Mod: Can Large Language Models Assist Content Moderation?

open access: yesCHI Extended Abstracts
Content moderation is critical for maintaining healthy online spaces. However, it remains a predominantly manual task. Moderators are often exhausted by low moderator-to-posts ratio.
Mahi Kolla   +3 more
semanticscholar   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Workaholism and Sleep Disorders in Employees: The Moderator Roles of Workaholism in the Relationships between Insomnia and Affective Symptoms

open access: yesTürk Uyku Tıbbı Dergisi
Objective: Sleep disorders are a growing concern in occupational health due to their strong associations with emotional distress and impaired functioning.
Yağmur Nalbantoğlu   +1 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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