Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
Traditional or Modern Contraception? Association Between Health Worker Contact and Contraceptive Choice in India: Findings From NFHS 2019-2021. [PDF]
Bhan N +6 more
europepmc +1 more source
A BN@G‐POSS/EP nanocomposite is developed for high‐frequency transformer insulation in power electronic transformers. Through synergistic interface engineering, it simultaneously enhances thermal conductivity, reduces viscosity, and improves electro‐thermal stability.
Jun Jiang +6 more
wiley +1 more source
Progress in family planning in Sierra Leone: a mixed-methods case study. [PDF]
Amara PS +15 more
europepmc +1 more source
Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang +6 more
wiley +1 more source
Community-level variations in contraceptive use among women in union and those not in union: a comparative study of 35 sub-Saharan African countries. [PDF]
Debere HR, Guo S, Zheng X.
europepmc +1 more source
Conventional passive radiative cooling films rely on costly feedstocks and energy‐intensive fabrication, with poor end‐of‐life compatibility in agriculture. To address this challenge, a sustainable radiative cooling mulch (SRCM) is developed from waste maize leaves via spontaneous hydrogen‐bond self‐assembly.
Hao Li +13 more
wiley +1 more source
AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi +4 more
wiley +1 more source
Validation and utility of the French version of the Unified Multidimensional Calling Scale (UMCS-22) for stipended volunteer firefighters. [PDF]
Burakova M.
europepmc +1 more source

