Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
Animal Models and Experimental Medicine, EarlyView.We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source
Use of modern contraceptive methods among women of childbearing age attending maternal and child health services in Abidjan and Agboville (Cote d'Ivoire). [PDF]
BMC Public HealthEssis EML, Cissé K, Kpebo DOD.
europepmc +1 more source
Differences in cynomolgus macaque populations used for infectious disease research
Animal Models and Experimental Medicine, EarlyView.Cynomolgus macaques, a species of Old World primate native to southeastern and eastern Asia and the island of Mauritius, are one of the most important nonhuman primate models for infectious disease. Research into the population genetics of cynomolgus macaques has found significant differences between macaques native to different areas, particularly ...
Darcy Quist +4 more
wiley +1 more source
Molecular surveillance of the Plasmodium falciparum Pfmdr1 N86Y mutation linked to antimalarial drug resistance in Mbouda, Cameroon. [PDF]
Trop Dis Travel Med VaccinesNadia NAC +10 more
europepmc +1 more source
Journal of Applied Polymer Science, EarlyView.DIW 3D printing of silicone materials can be optimized by controlling their gelling behavior or curing mechanism with carbon nanotubes. This precision control results in high‐performance elastomer materials and is a model study for characterization methods.
G. M. Fazley Elahee +5 more
wiley +1 more source
Involuntary treatment for substance use: application of Kass' ethical framework to Alberta's <i>Compassionate Intervention Act</i>. [PDF]
CMAJWilson P, Larson B, Colizza K.
europepmc +1 more source
Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola
The Anatomical Record, EarlyView.Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum +3 more
wiley +1 more source
Prevalence of housing structure and quality indicators in India: An assessment of changes across 720 districts between 2016 and 2021. [PDF]
SSM Popul HealthJain A +3 more
europepmc +1 more source
The Anatomical Record, EarlyView.Abstract The three mammalian auditory ossicles enhance sound transmission from the tympanic membrane to the inner ear. The anterior anchoring of the malleus is one of the key characters for functional classification of the auditory ossicles. Previous studies revealed a medial outgrowth of the mallear anterior process, the processus internus ...
Franziska Fritzsche +2 more
wiley +1 more source
Enhancing the Performance and Reliability of an Automotive Reed Sensor Through Spring Integration and Advanced Manufacturing. [PDF]
Sensors (Basel)Farooq U +7 more
europepmc +1 more source