Results 31 to 40 of about 204,126 (298)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Modern Foreign Languages Get a Voice: The Role of Journals in the Reform Movement [PDF]

open access: yes, 2018
This chapter investigates the significance of specialized journals for the development of modern language teaching. It begins by explaining the development of language journals up to the point at which language teaching reform really took off with the ...
Linn, A.
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Socio-psychological view on the modern charismatic movement

open access: yesУкраїнське Pелігієзнавство, 2001
The emergence and activity of neo-religious groups, to which we also refer to charismatic churches, is a manifestation of one of the global trends of modern religious life-traditional encounter with a new, still unknown.
Vita Volodymyrivna Tytarenko
doaj   +1 more source

Movement experience in modern dance : a phenomenological inquiry [PDF]

open access: yes, 1984
The movement phenomenon in modern dance was studied from the viewpoint of experiences using phenomenology as the research approach. The inquiry is focused on how students in higher education make meaning out of the dance movement experience. This inquiry
Braxton, Jean Patricia Bailey   +1 more
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Housing for the greatest number

open access: yesDocomomo Journal, 2021
Addressing a broader vision, entitled “Housing for All”, this issue is dedicated to the welfare era, when governments across the world established ambitious housing programs to provide housing for the greatest number and improve the citizens’ living ...
Ana Tostões
doaj   +1 more source

Re-reading Mary Wigman's Hexentanz II (1926): the influence of the non-Western 'Other' on movement practice in early modern 'German' dance

open access: yes, 2013
This paper provides a re-reading of Mary Wigman’s Hexentanz II (‘Witch Dance’, 1926), emphasising the social and aesthetic conditions in which she created dance works.
Weir, Lucy, Tsitsou, Lito
core   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

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