Results 51 to 60 of about 13,646,246 (214)

Electron-beam FLASH whole brain irradiation induced a unique changes of intestinal flora

Molecular Medicine
Background Whole-brain radiotherapy (WBRT) is an important way to treat multiple metastases. Ultra-high dose rate (FLASH) can avoid neurotoxicity caused by conventional irradiation, it has attracted much attention. This study aims to study the difference
Feifei Gao, Wei Cheng, Yanxi Ma, Boyi Yu, Xinle Lang, Xiaodong Jin, Jianxin Wang, Xianhong Liu, Cuixia Di, Hui Wang, Fei Ye, Ting Zhao, Weiqiang Chen, Qiang Li   +13 more
doaj   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Regulating the metabolic flux of pyruvate dehydrogenase bypass to enhance lipid production in Saccharomyces cerevisiae

Communications Biology
To achieve high efficiency in microbial cell factories, it is crucial to redesign central carbon fluxes to ensure an adequate supply of precursors for producing high-value compounds.
Cairong Lei, Xiaopeng Guo, Miaomiao Zhang, Xiang Zhou, Nan Ding, Junle Ren, Meihan Liu, Chenglin Jia, Yajuan Wang, Jingru Zhao, Ziyi Dong, Dong Lu   +11 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Furfural tolerance of mutant Saccharomyces cerevisiae selected via ionizing radiation combined with adaptive laboratory evolution

Biotechnology for Biofuels and Bioproducts
Background Lignocellulose is a renewable and sustainable resource used to produce second-generation biofuel ethanol to cope with the resource and energy crisis.
Junle Ren, Miaomiao Zhang, Xiaopeng Guo, Xiang Zhou, Nan Ding, Cairong Lei, Chenglin Jia, Yajuan Wang, Jingru Zhao, Ziyi Dong, Dong Lu   +10 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

O lugar da análise do comportamento no debate científico contemporâneo

Psicologia: Teoria e Pesquisa
A ciência sofreu várias transformações ao longo da história. Assiste-se no terreno científico-filosófico contemporâneo a mais uma mudança: a crise do modelo de ciência moderno e a emergência de uma diferente proposta científica, a ciência pós-moderna ...
Carolina Laurenti
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Heavy N+ ion transfer in doubly charged N2Ar van der Waals cluster

Nature Communications, 2020
There are multiple ways by which energy and charge transfer occur in weakly bound systems. Here the authors reveal a heavy ion N+ transfer in a doubly charged Van der Waals cluster produced in collisions of the highly charged Ne8+ ion with N2Ar, leading ...
XiaoLong Zhu, XiaoQing Hu, ShunCheng Yan, YiGeng Peng, WenTian Feng, DaLong Guo, Yong Gao, ShaoFeng Zhang, Amine Cassimi, JiaWei Xu, DongMei Zhao, DaPu Dong, Bang Hai, Yong Wu, JianGuo Wang, X. Ma   +15 more
doaj   +1 more source