Results 101 to 110 of about 176,324,123 (299)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

THE OPERATION MODES OPTIMIZATION OF THE NEUTRAL DISTRIBUTION NETWORKS

open access: yesNauka ta progres transportu, 2009
The variants of grounding the neutral wire of electric networks are considered and the recommendations are presented on increasing the level of operational reliability and electric safety of distribution networks with 6 kV voltage on the basis of ...
F. P. Shkarbets, A. I. Kovalov
doaj  

A Leakage-Resilient Mode of Operation [PDF]

open access: yes, 2009
A weak pseudorandom function (wPRF) is a cryptographic primitive similar to --- but weaker than --- a pseudorandom function: for wPRFs one only requires that the output is pseudorandom when queried on random inputs. We show that unlike "normal" PRFs, wPRFs are seed-incompressible, in the sense that the output of a wPRF is pseudorandom even if a bounded
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Cryptanalysis of Multiple Modes of Operation

open access: yes, 1994
In recent years, several new attacks on DES were introduced. These attacks have led researchers to suggest stronger replacements for DES, and in particular new modes of operation for DES.
Eli Biham
core  

CMOS Current-mode Operational Amplifier [PDF]

open access: yesESSCIRC '92: Eighteenth European Solid-State Circuits conference, 1992
A fully differential-input differential-output current-mode operational amplifier (COA) is described. The amplifier utilizes three second generation current-conveyors (CCII) as the basic building blocks. It can be configured to provide either a constant gain-bandwidth product in a fully balanced current-mode feedback amplifier or a constant bandwidth ...
openaire   +4 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

On the High-Density Modes of Operation in W7-AS

open access: yesFusion Science and Technology, 2004
A plausible physical explanation of a new advanced high-density H (HDH)-mode operational regime on the W7-AS stellarator is discussed. The HDH regime can be achieved only under a high rate of particle fueling during the starting phase of the discharge.
Igitkhanov, Yu. L.   +2 more
openaire   +5 more sources

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