Results 131 to 140 of about 6,177,010 (327)

Computer-aided design of high-contact-ratio gears for minimum dynamic load and stress [PDF]

open access: yes
A computer aided design procedure is presented for minimizing dynamic effects on high contact ratio gears by modification of the tooth profile. Both linear and parabolic tooth profile modifications of high contact ratio gears under various loading ...
Lee, Chinwai   +3 more
core   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Study of structural, surface energies, and tribomechanical properties of thermoplastics irradiated by electron beam

open access: yesMaterials Research Express
This study investigates the effects of electron irradiation on the structural, surface energy, and tribomechanical properties of two key thermoplastics: polyetheretherketone (PEEK) and polytetrafluoroethylene (PTFE).
Bauyrzhan Rakhadilov   +5 more
doaj   +1 more source

Detection of dry season anomaly using radiosonde data during intensive observation period (IOP) in 2017

open access: yesMATEC Web of Conferences, 2018
In the period between July - August 2017, Indonesia experiences drought which was caused by The Australian Monsoon wind. Radiosonde data obtained from launches conducted at the Palembang Meteorological Station during the IOP of 17 July - 16 August 2017 ...
Mariana S. Rini   +9 more
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Microphysical Characteristics of Melting Layers in North China Revealed by Aircraft and Radar

open access: yesRemote Sensing
The microphysical processes within the melting layer (ML) of stratiform clouds have been understudied, particularly regarding their intricate properties and behaviors.
Xiangfeng Hu   +8 more
doaj   +1 more source

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