Results 41 to 50 of about 1,777,350 (269)

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Climate change impacts on precipitation and water resources in Northwestern China

open access: yesFrontiers in Environmental Science
A statistical analysis is conducted on the hourly precipitation at 105 national meteorological stations in the Xinjiang region of China from 2011 to 2020.
Bohua Zheng   +10 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Cloud Observation by Aircraft During Dust Storms

open access: yes应用气象学报
Aerosols influence cloud microphysical properties by acting as cloud condensation nuclei and ice nuclei. Aerosols have the potential to modify the location and intensity of precipitation by changing cloud properties.
Ma Xincheng   +4 more
doaj   +1 more source

Circadian protein BMAL1 promotes breast cancer cell invasion and metastasis by up-regulating matrix metalloproteinase9 expression

open access: yesCancer Cell International, 2019
Background Metastasis is an important factor in the poor prognosis of breast cancer. As an important core clock protein, brain and muscle arnt-like 1 (BMAL1) is closely related to tumorigenesis.
Jian Wang   +9 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Aircraft Observations of Aerosol Properties and Their Impact on Cloud Droplets in Gansu Province

open access: yes应用气象学报
Aerosol-cloud interaction has significant influences on radiation balance, water cycle and energy cycle of earth-air system. Sources of aerosols in Gansu Province are complex, involving both natural and anthropogenic activities. Based on typical aircraft
Wang Yanfeng   +6 more
doaj   +1 more source

Analysis of radar echo and lightning characteristics in a multi-cell hail weather event

open access: yes暴雨灾害, 2020
Using Doppler radar data, 3-D lightning monitoring network data and MICAPS converntional observtation data, the radar echo evolution and lightning characteristics of a multi-cell hail weather event in central Guizhou on 5 April 2017 were analyzed.
Yong ZENG   +5 more
doaj   +1 more source

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