Results 61 to 70 of about 7,502,218 (147)

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, Volume 13, Issue 9, 13 February 2026.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

The Influence of Psychological Stress and Stress‐Related Disorders in the Treatment Outcome of Periodontitis: A Systematic Review and Meta‐Analysis

Journal of Clinical Periodontology, Volume 52, Issue 12, Page 1760-1778, December 2025.
ABSTRACT Background and Objective In humans 16 years and above with periodontitis (Population), how do psychological stress and stress‐related disorders (PSRD; Exposure) compared to those without PSRD (Comparison) affect clinical attachment level (CAL) upon periodontitis treatment (Outcome), as observed in experimental studies or descriptive pre–post ...
Erik Klepsland Mauland, Sudan Prasad Neupane   +1 more
wiley   +1 more source

Assessment of patients’ dental anxiety levels in the context of infectious diseases: development and validation of Musa Kazim’s Dental Anxiety Scale (MK-DAS)

BMC Psychology
Objectives The study aimed to develop and validate a new scale called Musa Kazim’s Dental Anxiety Scale (MK-DAS) to measure dental anxiety in relation to infectious diseases.
Musa Kazim Ucuncu, Merve Yildirim Ucuncu
doaj   +1 more source

Impact of non-surgical periodontal treatment on dental anxiety: A comparative study on patients with periodontitis

Journal of Dental Sciences
Background/purpose: Dental anxiety is prevalent and may result in the avoidance of periodontal therapy and maintenance. This study aimed to explore the impact of non-surgical periodontal treatment (NSPT) on dental anxiety among patients with ...
Jun-Chin Tu, Cheng-Yang Chiang, Hsien-Chung Chiu, Fu-Gong Lin, I-Shiang Tzeng, Earl Fu   +5 more
doaj   +1 more source

Community Engagement Studio as a Strategic Tool for Tailoring a Survey on Dental Care Access Among Adolescents

Journal of Public Health Dentistry, Volume 85, Issue 4, Page 352-360, Autumn 2025.
ABSTRACT Objectives The Community Engagement (CE) Studio aimed to provide feedback on a survey related to dental care access among adolescents. This approach allowed the research team to ensure that the survey integrated both the investigator's perspective and direct input from the community, ensuring the survey was clear, relevant, and accessible to ...
Rubelisa C. G. de Oliveira, Hassan Khalid, Grace McKenzie, Laurene Tumiel‐Berhalter, Jessica S. Kruger   +4 more
wiley   +1 more source

Dental anxiety among patients visiting a University Dental Centre [PDF]

, 2012
Objective: Fearful individuals often avoid care despite extensive dental needs and anxious patients feel more pain and of longer duration than less anxious patients.
Adeyemi, BF, Kolude, B, Ajayi, DM, Arigbede, AO   +3 more
core   +1 more source

Electrodermal Activity for Quantitative Assessment of Dental Anxiety

Journal of Sensor and Actuator Networks
In spite of the development in technology and the recent innovations in dentistry, dental anxiety remains a common issue, and accurately assessing it is challenging due to reliance on patients’ self-reports, which are often biased.
Dindar S. Bari, Mohammed Noor S. Rammoo, Ardawan A. Youssif, Hoger M. Najman, Haval Y. Yacoob Aldosky, Christian Tronstad, Jie Hou, Ørjan G. Martinsen   +7 more
doaj   +1 more source

Determining the Effect of Video Information on the Dental Anxiety Levels of the Endodontic Patients: A Randomised Clinical Trial

Journal of Oral Rehabilitation, Volume 52, Issue 11, Page 1933-1944, November 2025.
ABSTRACT Objective The present study assessed the effectiveness of pretreatment education in the form of Visual Video Information (VVI) on the anxiety levels of patients during endodontic treatment steps. Methods Patients (n = 120) having single‐rooted teeth with a single root canal diagnosed with asymptomatic irreversible pulpitis and/or pre ...
Şule Anatürk, Hicran Dönmez Özkan, İlkim Pınar Saral, Tuna Çakar   +3 more
wiley   +1 more source

Prevalence of dental anxiety and its associated factors among patients visiting tertiary care dental hospital in Kathmandu, Nepal: a cross-sectional study

BMJ Open
Background Dental anxiety, affecting 15.3% of adults globally, is more common in younger people and women. It often leads to avoiding dental visits, which worsens oral health.
Archana Shah, Krishna Subedi, Monika Kumal, Kanaklata Karn, Kiran Kandel, Alina Paneru   +5 more
doaj   +1 more source

PENGARUH AROMATERAPI CITRONELLA (Cymbopogon nardus) INHALASI TERHADAP PENURUNAN TINGKAT KECEMASAN PASIEN SEBELUM EKSTRAKSI GIGI DITINJAU DARI MDAS (Modified Dental Anxiety Scale) (Penelitian di RSGM Soelastri UMS) [PDF]

, 2020
Latar Belakang: Ekstraksi gigi adalah proses pencabutan gigi dari dalam soket dan tulang alveolar yang sering dilakukan oleh dokter gigi. Perawatan ini sering kali menimbulkan kecemasan.
Hutami, Amelia Rizky, Oktaviani, Rizki, , drg. Nina Runting, Sp. BMM   +2 more
core   +1 more source