Results 61 to 70 of about 17,412 (237)

Multi‐omic profiling reveals immune cell priming signature linked to lupus prognosis

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is a multi‐organ disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith, Dominic Sinibaldi, Saifur Rahman, Chia‐Chien Chiang, Anna M. Hansen, Jill Henault, Carlos P. Roca, Shu Wang, Kamelia Zerrouki, Rebecca Filippi, Christopher Groves, Zerai Manna, Jun Chu, Michael Davis, Sarthak Gupta, Christopher Morehouse, Melissa de los Reyes, Rachel Ettinger, Roland Kolbeck, Mariana J. Kaplan, Miguel A. Sanjuan, Richard M. Siegel, Sarfaraz A. Hasni, Kerry A. Casey   +23 more
wiley   +1 more source

Smart Energy Management of Residential Microgrid System by a Novel Hybrid MGWOSCACSA Algorithm

Energies, 2020
Optimal scheduling of distributed energy resources (DERs) of a low-voltage utility-connected microgrid system is studied in this paper. DERs include both dispatchable fossil-fueled generators and non-dispatchable renewable energy resources.
Bishwajit Dey, Fausto Pedro García Márquez, Sourav Kr. Basak   +2 more
doaj   +1 more source

Single‐cell level characterization of B cell depletion and repopulation following rituximab in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Optimal Number, Location, and Size of Distributed Generators in Distribution Systems by Symbiotic Organism Search Based Method [PDF]

, 2017
This paper proposes an approach based on the Symbiotic Organism Search (SOS) for optimal determining sizing, siting, and number of Distributed Generations (DG) in distribution systems. The objective of the problem is to minimize the power loss of the
Nguyen-Phuoc, Tri, Tran-The, Tung, Vo, Dieu Ngoc   +2 more
core   +2 more sources

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Simultaneous lesion and neuroanatomy segmentation in Multiple Sclerosis using deep neural networks [PDF]

, 2019
Segmentation of both white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis.
Aschwanden, Fabian, Chan, Andrew, Grunder, Lorenz, McKinley, Richard, Muri, Raphaela, Reyes, Mauricio, Rummel, Christian, Salmen, Anke, Verma, Rajeev, Wagner, Franca, Weisstanner, Christian, Wepfer, Rik, Wiest, Roland   +12 more
core   +2 more sources

Tracking Climate and Environmental Attention: A News‐Based Composite Index

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study introduces the Climate and Environmental Attention Index, a composite indicator that tracks media attention to climate and environmental issues. Based on the Semantic Brand Score, the proposed index extracts significant signals from unstructured text, going beyond traditional measures of word frequency and sentiment.
Gianna Figà‐Talamanca, Andrea Fronzetti Colladon, Barbara Guardabascio, Ludovica Segneri   +3 more
wiley   +1 more source

Strengthening urban resilience in China through underground infrastructures management: Addressing global climate challenges with technological solutions

Deep Underground Science and Engineering, EarlyView.
This paper explores how climate‐resilient technologies, such as smart grids, digital twins, and self‐healing materials, can enhance urban resilience. It highlights the urgent need for proactive planning, public‐private collaboration, and data‐driven innovation to future‐proof underground infrastructure amid accelerating climate and urban pressures ...
Kai Chen Goh, Tonni Agustiono Kurniawan, Christia Meidiana, Abdelkader Anouzla, Faissal Aziz, Imran Ali, Joan Cecilia C. Casila, M. Imran Khan, Dongdong Zhang, Meihui Jiang, Mohd Hafiz Dzarfan Othman, Md Munir Hayet Khan, Kasun Kumara Dissanayake   +12 more
wiley   +1 more source

WGC: Hybridization of exponential grey wolf optimizer with whale optimization for data clustering

Alexandria Engineering Journal, 2018
Data present in abundance increases the complexity of handling them, which affects the effective decision-making process. Hence, data clustering gains remarkable importance in knowledge extraction and an efficient clustering method promotes the efficient
Amolkumar Narayan Jadhav, N. Gomathi
doaj   +1 more source

Metaheuristic design of feedforward neural networks: a review of two decades of research [PDF]

, 2017
Over the past two decades, the feedforward neural network (FNN) optimization has been a key interest among the researchers and practitioners of multiple disciplines.
Abbass, Abraham, Ackley, Ajith Abraham, Akhand, Alba, Ali Ahmadi, Almeida, Alvarez, Amari, Andersen, Angeline, Arifovic, Augusteijn, Azimi-Sadjadi, Bakker, Baranyi, Battiti, Bertsekas, Bishop, Bland, Bousquet, Boussaid, Breiman, Brownlee, Carvalho, Chandra, Charalambous, Chen, Chen, Chen, Chen, Cho, Chrisley, Coello, Cortes, Costa, Cruz-Ramírez, Cybenko, Da, da Silva, Dai, Das, Das, Davis, de Albuquerque Teixeira, Deneubourg, Dhahri, Diebold, Ding, Ditzler, Dominey, Donate, Dorigo, Dumont, Engel, Fahlman, Feo, FernandezCaballero, Fister, Fletcher, Fogel, Fogel, Fontanari, Formato, Frean, Fukumizu, Fullér, Furtuna, Garcia-Pedrajas, García-Pedrajas, García-Pedrajas, Gaspar-Cunha, Geem, Geman, Gershenfeld, Ghalambaz, Girosi, Giustolisi, Glover, Goh, Goldberg, Gori, Gorin, Green, Grossberg, Hagan, Hansen, Haykin, Haykin, Hernández, Hestenes, Hinton, Hinton, Hinton, Hirose, Ho, Holland, Hopfield, Hornik, Hornik, Huang, Huang, Huang, Huang, Huang, Igel, Ilonen, Irani, Irani, Islam, Jacobs, Jain, Jain, Jin, Juang, Kaelbling, Karaboga, Karpat, Kennedy, Khan, Khan, Kim, Kim, Kim, Kim, Kiranyaz, Kirkpatrick, Kitano, Kitano, Kohonen, Kolmogorov, Kordík, Kouda, Koza, Kulluk, Kŭrková, Lam, Larrañaga, LeCun, Lera, Leshno, Leung, Leung, Lewenstein, Li, Lin, Lin, Ling, Lippmann, Liu, Liu, Lowe, Ludermir, Mahdavi, Maniezzo, March, Marquardt, Martínez-Muñoz, Mazurowski, McCulloch, Menczer, Merrill, Metropolis, Minku, Minsky, Mirjalili, Mirjalili, Mitra, Mjolsness, Mladenović, Moriarty, Murray, Nakama, Nandy, Narayanan, Natschläger, Nedjah, Niranjan, Niu, Nolfi, Oh, Ojha, Osman, Pan, Passino, Pearce, Pencina, Peng, Pettersson, Pipino, Polikar, Prechelt, Prisecaru, Puig, Rashedi, Reed, Ritchie, Rosenblatt, Rumelhart, Rumelhart, Saad, Salajegheh, Sarkar, Schaffer, Schapire, Schmidhuber, Schwefel, Sejnowski, Selmic, Sexton, Sexton, Sexton, Shang, Sharma, Sietsma, Simovici, Sivagaminathan, Slowik, Socha, Socha, Sokolova, Sporea, Stanley, Storn, Sum, Sörensen, Tang, Tayefeh Mahmoudi, Toh, Tong, Trelea, Trentin, Tsai, Tsai, Tsoulos, Twomey, Ulagammai, Van den Bergh, van der Voet, Varun Kumar Ojha, Venkadesh, Ventura, Vieira, Václav Snášel, Wand, Wang, Wessels, Weyland, Whitley, Widrow, Wiegand, Wilson, Wolpert, Wolpert, Xi-Zhao, Yaghini, Yang, Yang, Yao, Yao, Yao, Yao, Yao, Yao, Yao, Ye, Yin, Yusiong, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhou, Zhou, Zikopoulos, Zăvoianu, Černỳ   +279 more
core   +2 more sources