Results 21 to 30 of about 1,560,616 (133)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Epileptic dyskinetic encephalopathy in KBG syndrome: Expansion of the phenotype

Epilepsy & Behavior Reports
KBG syndrome is characterised by developmental delay, dental (macrodontia of upper central incisors), craniofacial and skeletal anomalies. Since the identification of variants in the gene (ANKRD11) responsible for KBG syndrome, wider phenotypes are ...
Eoin P. Donnellan, Kathleen M. Gorman, Amre Shahwan, Nicholas M. Allen   +3 more
doaj   +1 more source

Polysaccharide - Modified MMT/ Modified MMT/ Polysaccharide – MNP, Lignin - Modified MMT Nanocomposites Verses Polyethyleneimineimine- Modified MMT-: A Comparative Analysis of Sustained Pesticide Delivery [PDF]

, 2021
Highlights: • At the nanoscale, the characteristics of a material can alter dramatically. With only a reduction in size and no change to the substance itself, materials can display new qualities.
RITU, Mahajan
core   +2 more sources

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Quantification of hypsarrhythmia in infantile spasmatic EEG:a large cohort study [PDF]

Infantile spasms (IS) is a neurological disorder causing mental and/or developmental retardation in many infants. Hypsarrhythmia is a typical symptom in the electroencephalography (EEG) signals with IS.
Qinman Wu, Lin Xu, Xu, Lin, He, Wenyuan, Lyu, Peize, Peize Lyu, Ruisheng Su, Zhao, Zihao, Yumei Yan, Yuanning Li, Hu, Xindan, Yan, Yumei, Guo, Qiongru, Tao Tan, Xiaoqiang Wang, Qiongru Guo, Wang, Xiaoqiang, Zihao Zhao, Xindan Hu, Dake He, Ruolin Hou, He, Dake, Wenyuan He, Su, Ruisheng, Li, Yuanning, Hou, Ruolin, Wu, Qinman, Tan, Tao   +27 more
core   +1 more source

Impact of vigabatrin on risk of relapse of infantile spasms

Epilepsia Open, EarlyView.
Abstract Objective Vigabatrin is an effective treatment for infantile epileptic spasms syndrome (IESS), but relapse remains a clinical challenge. The ideal dose and duration of treatment after response are unknown. We set out to identify treatment‐related predictors of IESS relapse after initial vigabatrin response. Methods We conducted a retrospective
Yaretson I. Carmenate, Hayoung E. Ahn, Haley R. Peters, Hiroki Nariai, Rajsekar R. Rajaraman, Shaun A. Hussain   +5 more
wiley   +1 more source

ACTH Therapy in Epileptic Spasms without Hypsarrhythmia

, 2005
The short and long-term effects of adrenocorticotrophic hormone (ACTH) in 30 children ages 11 to 86 months (median 29 months) with epileptic spasms (ES) without hypsarrhythmia were analyzed at Tokyo Women’s Medical University ...
J Gordon Millichap
core   +1 more source

Reliability of the modified Rankin Scale: a systematic review [PDF]

, 2009
<p><b>Background and Purpose:</b> A perceived weakness of the modified Rankin Scale is potential for interobserver variability. We undertook a systematic review of modified Rankin Scale reliability studies.</p> <p><b ...
Lees, K.R., Walters, M., Dawson, J., Quinn, T.J.   +3 more
core   +1 more source

Neuroimaging and neurophysiology in infantile‐onset epilepsy after neonatal stroke

Developmental Medicine &Child Neurology, EarlyView.
This population‐based retrospective cohort study of 55 newborn infants demonstrated that neonatal MRI and neonatal neurophysiology (amplitude‐integrated EEG, conventional EEG, and somatosensory evoked potentials) combined with follow‐up EEGs during the first year of life provide practical tools for identifying infants at the highest risk of developing ...
Sinikka La Grassa, Kirsi Mikkonen, Marjo Metsäranta, Sanna Toiviainen‐Salo, Sampsa Vanhatalo, Leena Lauronen, Päivi Nevalainen   +6 more
wiley   +1 more source

Persistence of Hypsarrhythmia in Children Beyond the Age of Three Years

, 2011
Occurrence of hypsarrhythmia after the age of 3 years is rare. The objective of this study is to describe a group of patients who have persistence of hypsarrhythmia after the age of 3 years.
Ignacio Valencia, Divya S. Khurana, Agustin Legido, Karen S. Carvalho, Kandan Kulandaivel, Joseph J. Melvin   +5 more
core   +1 more source