Results 241 to 250 of about 166,348,124 (287)

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Bone stress injury recovery and return to sport in runners: a multi-site prospective observational cohort study protocol across the USA and Canada. [PDF]

BMJ Open
Popp KL, Whitcomb E, Hahn ME, Stellingwerff T, Guldberg RE, Kraus E, Bouxsein ML, Ackerman KE.   +7 more
europepmc   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

A Sufficiently Effective and Low-Risk Plane Block: A Randomized Controlled Trial Evaluating the Modified Parasternal Block in Off-Pump Coronary Artery Bypass Grafting with Sternotomy. [PDF]

J Clin Med
Feng X, Kang R, Huang L, Yan F, Yao D, Li X.   +5 more
europepmc   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Reconstructing IDF curves from daily rainfall records in data-scarce regions: A statistical method based on temporal disaggregation and gumbel modeling. [PDF]

PLoS One
Molino J, Martí-Fis H, Rodriguez-López Y.   +2 more
europepmc   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Lateral extra-articular procedures in primary anterior cruciate ligament reconstruction reduce graft failure rates in elite and competitive athletes: A systematic review. [PDF]

J Exp Orthop
Kratochwil L, Kienberger S, Deichsel A, Gotterbarm T, Winkler PW.   +4 more
europepmc   +1 more source

ACL injuries in skeletally immature athletes. [PDF]

Front Pediatr
Ina JG, Kocher MS.
europepmc   +1 more source

Predictors and Consequences of Serious Adverse Events in Patients Treated With Thrombolysis: A Prespecified Secondary Analysis of the AcT Trial. [PDF]

J Am Heart Assoc
Appoo A, Ignacio K, Doolan C, Bala F, Almekhlafi M, Buck BH, Tkach A, Catanese L, Swartz RH, Sajobi TT, Ganesh A, Menon BK, Singh N.   +12 more
europepmc   +1 more source