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Modular design of synthetic receptors for programmed gene regulation in cell therapies. [PDF]

open access: yesCell, 2022
Synthetic biology has established powerful tools to precisely control cell function. Engineering these systems to meet clinical requirements has enormous medical implications. Here, we adopted a clinically driven design process to build receptors for the
Zhu I   +9 more
europepmc   +4 more sources

Modular Design in Triboelectric Sensors: A Review on the Clinical Applications for Real-Time Diagnosis [PDF]

open access: yesSensors, 2023
Triboelectric nanogenerators (TENGs) have garnered considerable interest as a promising technology for energy harvesting and stimulus sensing. While TENGs facilitate the generation of electricity from micro-motions, the modular design of TENG-based ...
Zequan Zhao   +7 more
doaj   +3 more sources

Modular Design of Membrane-Active Antibiotics: From Macromolecular Antimicrobials to Small Scorpionlike Peptidomimetics. [PDF]

open access: yesJ Med Chem, 2021
Infections caused by multidrug-resistant bacteria have emerged in recent decades, leading to escalating interest in host defense peptides (HDPs) to reverse this dangerous trend.
Wang M   +8 more
europepmc   +2 more sources

A Modular Design for Distributed Measurement of Human-Robot Interaction Forces in Wearable Devices. [PDF]

open access: yesSensors (Basel), 2021
Measurement of interaction forces distributed across the attachment interface in wearable devices is critical for understanding ergonomic physical human–robot interaction (pHRI).
Ghonasgi K   +3 more
europepmc   +2 more sources

Supporting `Design for Re-use' with Modular Design [PDF]

open access: yesConcurrent Engineering, 2007
Engineering design reuse refers to the utilization of any knowledge gained from the design activity to support future design. As such, engineering design reuse approaches are concerned with the support, exploration, and enhancement of design knowledge prior, during, and after a design activity. Modular design is a product structuring principle whereby
Meehan, J.S.   +2 more
openaire   +6 more sources

Rational modular design of metabolic network for efficient production of plant polyphenol pinosylvin. [PDF]

open access: yesSci Rep, 2017
Efficient biosynthesis of the plant polyphenol pinosylvin, which has numerous applications in nutraceuticals and pharmaceuticals, is necessary to make biological production economically viable.
Wu J   +5 more
europepmc   +2 more sources

Modular design patterns for hybrid learning and reasoning systems [PDF]

open access: yesApplied intelligence (Boston), 2021
The unification of statistical (data-driven) and symbolic (knowledge-driven) methods is widely recognized as one of the key challenges of modern AI. Recent years have seen a large number of publications on such hybrid neuro-symbolic AI systems.
M. V. Bekkum   +4 more
semanticscholar   +1 more source

Design optimisation of TPU modular footwear for sustainable fashion: a South African Fashion Week case study, 2023 [PDF]

open access: yesMATEC Web of Conferences, 2023
The fashion industry is continuously evolving, and Thermoplastic Polyurethane (TPU) produced modular footwear is emerging as a trend for sustainability. This study aims to optimise the design of TPU modular fashion footwear for the South African fashion ...
Havenga Sarel, van der Walt Philip
doaj   +1 more source

Modularisation Strategies for Individualised Precast Construction—Conceptual Fundamentals and Research Directions

open access: yesDesigns, 2023
Modular precast construction is a methodological approach to reduce environmental impacts and increase productivity when building with concrete. Constructions are segmented into similar precast concrete elements, prefabricated with integrated quality ...
Lothar Kolbeck   +19 more
doaj   +1 more source

Modularized robot machining system with scalability, portability and parallelism Modular design for machine tool to proove concept and drilling experiment using a general purpose robot

open access: yesNihon Kikai Gakkai ronbunshu, 2022
Existing manufacturing systems based on processes involving the transportation of workpiece are not suitable for large products such as air mobility. We have previously proposed a novel manufacturing system, “Modularized-Structure and Multiple-points ...
Takehito YOSHIDA   +3 more
doaj   +1 more source

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