Results 71 to 80 of about 9,578,430 (287)

Implementing Immersive Worlds for Metaverse-Based Participatory Design through Photogrammetry and Blockchain

ISPRS International Journal of Geo-Information
This paper explores participatory design methods for the interconnection of digital recording techniques, like digital photogrammetry and Gaussian splatting, with emerging domains such as the metaverse and blockchain technology.
Nikolai Abramov, Havana Lankegowda, Shunwei Liu, Luigi Barazzetti, Carlo Beltracchi, Pierpaolo Ruttico   +5 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Design, Performance Testing, and Experimental Validation of Modular Soft Robots Based on Thin-Film Actuators

Actuators
Currently, soft robots face challenges such as low motion efficiency, susceptibility to damage in traditional silicone materials, and difficulty in achieving reproducible manufacturing.
Anqi Guo, Zhiwei Ji, Siqi Yu, Wenlong Xie, Xiangchen He, Guoqing Jin   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Realising the open virtual commissioning of modular automation systems [PDF]

, 2011
To address the challenges in the automotive industry posed by the need to rapidly manufacture more product variants, and the resultant need for more adaptable production systems, radical changes are now required in the way in which such systems are ...
Jain, Atul, Lee, Leslie J., Robert Harrison (263043), Park, Y., Harrison, Robert, Leslie J. Lee (7204337), Kong, Xiangyu, Bilal Ahmad (773365), Xiangjun Kong (145590), Ahmad, Bilal, Atul Jain (827616), Y. Park (7208792)   +11 more
core  

A Proposal for a Multi-Drive Heterogeneous Modular Pipe- Inspection Micro-Robot [PDF]

, 2008
This paper presents the architecture used to develop a micro-robot for narrow pipes inspection. Both the electromechanical design and the control scheme will be described. In pipe environments it is very useful to have a method to retrieve information of
Brunete González, Alberto, Torres Matesanz, José Emilio, Hernando Gutiérrez, Miguel, Gambao Galán, Ernesto   +3 more
core   +1 more source

Application of Supports Theory in Building Design: Multi-Dimensional Permeability and Spatial Structure in Versatile Community Centers

Buildings
With the evolution of social structure and the intensification of population aging, traditional community service centers struggle to meet residents’ complex needs due to their functional singularity and spatial rigidity.
Mingrui Zhang, Yang Yang, Chang Yi, Mingxuan Jia, Menglong Zhang, Qianru Yang   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

A generic framework for context-sensitive analysis of modular programs [PDF]

, 2004
Context-sensitive analysis provides information which is potentially more accurate than that provided by context-free analysis. Such information can then be applied in order to validate/debug the program and/or to specialize the program obtaining ...
Stuckey, P.J., Peter J. Stuckey, Manuel V. Hermenegildo, Hermenegildo, Manuel V., Kim Marriott, Correas Fernandez, Jesús, Jesus Correas, Marriott, K., García de la Banda, M., Maria Garcia de la Banda, Francisco Bueno, German Puebla, María García De La B, Bueno Carrillo, Francisco, Puebla Sánchez, Alvaro Germán   +14 more
core   +1 more source