Modular Design of Mesoporous Silica Nanoparticles Enables Bioimaging, Dual Chemotherapy, and Combinatorial Gene Silencing in Triple-Negative Breast Cancer. [PDF]
Rebolledo LP +5 more
europepmc +1 more source
Machine Learning‐Assisted Inverse Design of Soft and Multifunctional Hybrid Liquid Metal Composites
A machine learning framework is presented for inverse design of synthesizable multifunctional composites containing both liquid metal and solid inclusions. By integrating physics‐based modeling, data‐driven prediction, and Bayesian optimization, the approach enables intelligent design of experiments to identify optimal compositions and realize these ...
Lijun Zhou +5 more
wiley +1 more source
Modular Design and Scaffold-Synthesis of Multi-Functional Fluorophores for Targeted Cellular Imaging and Pyroptosis. [PDF]
Zhang L +8 more
europepmc +1 more source
The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.
Romero-Romero S +11 more
europepmc +1 more source
This paper presents a digital microfluidics‐based technique for transferring and reconfiguring soft nanomembranes. Laser‐machined nanothin membranes are picked up, transported, and aligned via tailored surface tension and the actuation of water droplets, enabling the development of flexible electronics, the integration of functional materials on 3D ...
Quang Anh Nguyen +15 more
wiley +1 more source
Long-term migration of monoblock vs modular design in uncemented total knee arthroplasty: a secondary report of a randomized trial using radiostereometric analysis. [PDF]
Andersen MR +6 more
europepmc +1 more source
Sulfur fluoride exchange (SuFEx) is a powerful click platform, yet water‐compatible multifunctional linchpins remain elusive. Here, we report decagram‐scalable diazonium linchpins that enable rapid Pd‐catalyzed diversification and direct, catalyst‐free on‐DNA ligation in aqueous media.
Seok Ju Hong +5 more
wiley +1 more source
Modular design of bi- and multi-specific knob domain fusions. [PDF]
Kuravsky M +5 more
europepmc +1 more source
Modular design and self-assembly of multidomain peptides towards cytocompatible supramolecular cell penetrating nanofibers. [PDF]
Yang S, Dong H.
europepmc +1 more source
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang +9 more
wiley +1 more source

