Results 91 to 100 of about 10,207,502 (288)
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
AN ASSESSMENT OF METHODS TO SUPPORT THE DESIGN OF FUTURE ROBUST MODULAR PRODUCT ARCHITECTURES
, 2018 Modular product architectures enable not only a trade-off between the external variety demanded by the customer and the cost-causing internal variety, but also facilitate the ability to react on future requirement changes with less effort.
Krause, Dieter +3 more
core +1 more source
Reinventing the Freshwater Shelter
Cubic JournalAfter an era of rapid development, Hong Kong has reached a critical juncture at which urbanisation is saturated and in urgent need of transition. Hong Kong’s freshwater resources are in a state of scarcity due to its small geographical size, limited ...
Chen Xi
doaj +1 more source
FEBS Open Bio, EarlyView.A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li +7 more
wiley +1 more source
BiosensorsThis study presents a modular and scalable wearable functional near-infrared spectroscopy (fNIRS) system for high-resolution cerebral hemodynamic signal acquisition.
Mengjie Fang +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
Development of modular products under consideration of lightweight design
, 2011 Whether it is reduction of complexity during development or individual configuration for the consumer, modular products have many benefits throughout their product lifecycle. It is not surprising that many products are based on this principle. Along with
Gumpinger, Thomas, Krause, Dieter
core +1 more source
IEEE Open Journal of Power ElectronicsThis study proposes a modular, high-efficiency bidirectional isolated DC/DC converter with synchronous control. The converter adopts a modular design, where the power of a single module is 500 W.
Yu-En Wu, Po-Chun Liu
doaj +1 more source
FEBS Open Bio, EarlyView.Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley +1 more source
GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors
FEBS Open Bio, EarlyView.GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille +6 more
wiley +1 more source