Results 91 to 100 of about 114,053 (266)

A Comprehensive Decision-Making Approach for Strategic Product Module Planning in Mass Customization

open access: yesMathematics
This paper explores the integrated optimization of complex coupled industrial manufacturing systems and production strategies based on user customization needs. Two optimization metrics are considered: one is whether the production process of engineering
Shuo-Fang Liu   +2 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

An Automated Pipeline for Modular Space Planning Using Generative Design Within a BIM Environment

open access: yesApplied Sciences
Spatial Allocation Problems (SAP) in multistory buildings present significant challenges, as they require the simultaneous satisfaction of complex geometric constraints and conflicting functional requirements. To address this problem, this study proposes
Wonho Cho   +4 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

A modular casing while drilling rig for large-diameter horizontal boreholes for underground rescue

open access: yesMeitian dizhi yu kantan
ObjectiveOperations in a narrow space pose a challenge to rescue in the case of the collapse of mine roadways or tunnels. To address this challenge, this study developed a modular rescue casing while drilling (CwD) rig system for horizontal boreholes ...
Dong FAN   +6 more
doaj   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

Reinventing the Freshwater Shelter

open access: yesCubic Journal
After an era of rapid development, Hong Kong has reached a critical juncture at which urbanisation is saturated and in urgent need of transition. Hong Kong’s freshwater resources are in a state of scarcity due to its small geographical size, limited ...
Chen Xi
doaj   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

A Miniaturized and Modular Wearable Functional Near-Infrared Spectroscopy (fNIRS) Sensing Module for High-Density Cerebral Hemodynamic Monitoring

open access: yesBiosensors
This study presents a modular and scalable wearable functional near-infrared spectroscopy (fNIRS) system for high-resolution cerebral hemodynamic signal acquisition.
Mengjie Fang   +4 more
doaj   +1 more source

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