Results 171 to 180 of about 624,167 (298)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

DCAF16-Based Covalent Degradative Handles for the Modular Design of Degraders. [PDF]

ACS Cent Sci
Orr LM, Tomlinson SJ, Grupe HR, Lim M, Ho E, Yilmaz H, Zhou G, Leon B, Olzmann JA, Nomura DK.   +9 more
europepmc   +1 more source

Micropatterned Biphasic Printed Electrodes for High‐Fidelity on‐Skin Bioelectronics

Advanced Functional Materials, EarlyView.
Micropatterned biphasic printed electrodes achieve unprecedented skin conformity and low impedance by combining liquid‐metal droplets with microstructured 3D lattices. This scalable approach enables high‐fidelity detection of ECG, EMG, and EEG signals, including alpha rhythms from the forehead, with long‐term comfort and stability.
Manuel Reis Carneiro, Telmo Lopes, André F. Silva, Carmel Majidi, Mahmoud Tavakoli   +4 more
wiley   +1 more source

Modular Design of Mitochondrion-Targeted Iron Chelators Allows Highly Selective Antiparasitic Activity against Trypanosomes and Apicomplexan Parasites. [PDF]

ACS Infect Dis
Malych R, Bordat Y, Klanicová K, Arbon D, Zahedifard F, Šipková A, Drncová E, Levytska V, Mach J, Plutowski-Wrobel L, Machado M, Štursa J, Truksa J, Ganter M, Sojka D, Zoltner M, Besteiro S, Werner L, Sutak R.   +18 more
europepmc   +1 more source

Automatic modular design of robot swarms using behavior trees as a control architecture. [PDF]

PeerJ Comput Sci, 2020
Ligot A, Kuckling J, Bozhinoski D, Birattari M.   +3 more
europepmc   +1 more source

Modulating Two‐Photon Absorption in a Pyrene‐Based MOF Series: An In‐Depth Investigation of Structure–Property Relationships

Advanced Functional Materials, EarlyView.
This study investigates H4TBAPy‐based metal–organic frameworks (MOFs) ‐ NU‐1000, NU‐901, SrTBAPy, and BaTBAPy ‐ for multiphoton absorption (MPA) performance. It observes topology‐dependent variations in the 2PA cross‐section, with BaTBAPy exhibiting the highest activity.
Simon N. Deger, Helmy Pacheco Hernandez, Yang Cui, Hongxing Hao, Vanessa Ramm, David C. Mayer, Khai‐Nghi Truong, Roland A. Fischer, Jürgen Hauer, Mariana Kozlowska, Alexander Pöthig   +10 more
wiley   +1 more source

Testing the feasibility of multi-modular design in an HTR-PM nuclear plant. [PDF]

Nat Commun
Dong Z, Zhang Z, Dong Y, Shi L, Huang X, Zhu Y, Jiang D.   +6 more
europepmc   +1 more source

Selective Benzene Capture by Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
Metal‐organic frameworks (MOFs) hold significant potential for capturing benzene from air emissions and hydrocarbon mixtures in liquid phases. This capability stems from their precisely engineered structures, versatile chemistries, and diverse binding interactions.
Zongsu Han, Ankit Mondal, Jiatong Huo, Yihao Yang, Hong‐Cai Zhou   +4 more
wiley   +1 more source

Modular design of biomimetic electrospun keratin composites for tunable gaseous sorption inspired by reptile eggshells. [PDF]

Mater Today Bio
Maudens Y, Debruyn G, Loccufier E, Daelemans L, Savino E, Tonetti C, Vineis C, Varesano A, Shawkey MD, D'Alba L, De Clerck K.   +10 more
europepmc   +1 more source