Results 51 to 60 of about 576,932 (353)
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
A design method for modular energy-aware software [PDF]
, 2012 Nowadays achieving green software by reducing the overall energy consumption of the software is becoming more and more important. A well-known solution is to make the software energy-aware by extending its functionality with energy optimizers, which ...
Aksit, Mehmet +4 more
core +5 more sources
Traceability and modularity in software design [PDF]
Proceedings Ninth International Workshop on Software Specification and Design, 2002 A software design specification consists of a number of documents that describe various aspect of the design at different levels of detail, that are linked in many ways. This paper shows how different designs may use different modularization criteria, and how documents describing these designs may be linked in a coherent way, even if the designs use ...
openaire +3 more sources
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
Magnetocardiography with a modular spin-exchange relaxation free atomic magnetometer array
, 2011 We present a portable four-channel atomic magnetometer array operating in the spin exchange relaxation-free regime. The magnetometer array has several design features intended to maximize its suitability for biomagnetic measurement, specifically foetal ...
Bork J Hahlbohm H Klein R +9 more
core +1 more source
A holistic DC link architecture design method for multiphase Integrated Modular Motor Drives [PDF]
, 2019 This article describes a holistic DC link architecture design method that considers the end-application of the drive and its corresponding constraints e.g. the maximum battery ripple current for a battery-supplied inverter.
De Belie, Frederik +4 more
core +2 more sources
Molecular Oncology, EarlyView.Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley +1 more source
Modular digital computer system design [PDF]
, 1974 Automatically-Reconfigurable Modular Multiprocessor System (ARMMS) provides redundant processing with dynamic mode switching in real time. Design will provide higher computer capability than that presently available for same amount of hardware and will ...
core +1 more source
A framework for developing engineering design ontologies within the aerospace industry [PDF]
, 2014 This paper presents a framework for developing engineering design ontologies within the aerospace industry. The aim of this approach is to strengthen the modularity and reuse of engineering design ontologies to support knowledge management initiatives ...
Sanya, I. O., Shehab, Essam
core +1 more source
Modularization method based on creation of new layout structure
Nihon Kikai Gakkai ronbunshu, 2017 This paper describes a modularization method based on the creation of a new layout structure by combining topology optimization using beam elements and clustering analysis.
Hidekazu NISHIGAKI, Yasuo ASAGA
doaj +1 more source