Results 51 to 60 of about 14,308,933 (337)

Modular design through component abstraction [PDF]

open access: yesProceedings of the 2004 international conference on Compilers, architecture, and synthesis for embedded systems, 2004
Growing design sizes and shrinking time to market windows can only be met with drastically increased productivity. One way to obtain this is a smart reuse of intellectual property. This paper presents a methodology for modular design with the help of component abstraction.
Berner, David   +3 more
openaire   +2 more sources

Magnetocardiography with a modular spin-exchange relaxation free atomic magnetometer array

open access: yes, 2011
We present a portable four-channel atomic magnetometer array operating in the spin exchange relaxation-free regime. The magnetometer array has several design features intended to maximize its suitability for biomagnetic measurement, specifically foetal ...
Bork J Hahlbohm H Klein R   +9 more
core   +1 more source

Investigation of the energy performance of a novel modular solar building envelope [PDF]

open access: yes, 2017
The major challenges for the integration of solar collecting devices into a building envelope are related to the poor aesthetic view of the appearance of buildings in addition to the low efficiency in collection, transportation, and utilization of the ...
Jin, Hong   +4 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Long-Term Thermal Stability of Aerogel and Basalt Fiber Pipeline Insulation Under Simulated Atmospheric Aging

open access: yesEnergies
Thermal insulation materials used in power and industrial systems must maintain high performance under extreme environmental conditions. Among such materials, aerogel and basalt fiber are widely applied due to their low thermal conductivity and ease of ...
Irina Akhmetova   +9 more
doaj   +1 more source

Protocell design through modular compartmentalization [PDF]

open access: yesJournal of The Royal Society Interface, 2013
De novo synthetic biological design has the potential to significantly impact upon applications such as energy generation and nanofabrication. Current designs for constructing organisms from component parts are typically limited in scope, as they utilize a cut-and-paste ideology to create simple stepwise engineered protein-signalling pathways.
Miller, David   +7 more
openaire   +3 more sources

Accomplishing High-Level Tasks with Modular Robots

open access: yes, 2018
The advantage of modular self-reconfigurable robot systems is their flexibility, but this advantage can only be realized if appropriate configurations (shapes) and behaviors (controlling programs) can be selected for a given task.
Jing, Gangyuan   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

A modular design strategy considering sustainability and supplier selection

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2020
To utilize the residual value, which remains an idle asset and disposed product based on the circular economy package, the definition or clarification of such a value and the development of a scheme for such a reutilization is essential.
M. Inoue   +7 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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