Results 91 to 100 of about 14,033,253 (353)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The impact of modular product design on innovation compared with design from first principles
, 2010 The research looks at whether modular design methods can compromise innovation when compared with design from first principles. The questions that the authors investigated were: to what extent does modular product design restrict innovation in design? Is
Barker, Tom, Kokotovich, V, Barker, T
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Modular interactive architecture system design
, 2020 LAUREA MAGISTRALEIl lavoro mira ad esplorare la progettazione di sistemi di architettura interattiva modulare per soddisfare varie esigenze temporanee o di emergenza nei relativi contesti.
Feng, Wubing
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, 2012 Modular generator and converter topologies are being pursued for large offshore wind turbines to achieve fault tolerance and high reliability. A centralized controller presents a single critical point of failure which has prevented a truly modular and ...
Finney, Stephen J. +4 more
core +1 more source
Coiled coil protein origami: from modular design principles towards biotechnological applications.
Chemical Society Reviews, 2018 The design of new protein folds represents a grand challenge for synthetic, chemical and structural biology. Due to the good understanding of the principles governing its pairing specificity, coiled coil (CC) peptide secondary structure elements can be ...
Fabio Lapenta +3 more
semanticscholar +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Effect of femoral neck modularity upon the prosthetic range of motion in total hip arthroplasty [PDF]
, 2014 In total hip arthroplasty, aseptic loosening and dislocation are associated with not being able to achieve the correct prosthetic component orientation.
Griffin, Damian R. +2 more
core +1 more source
Journal of Intelligent ConstructionIn recent years, with the increasing demands for architectural design, the complexity of mechanical, electrical, and plumbing (MEP) systems has also increased, making the modular construction of integrated MEP systems a focal point of research in the ...
Xuefeng Zhao +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
O método do desdobramento da função modular no projeto e manufatura sustentável de produtos: aplicação em uma empresa do setor metal-mecânico [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia MecânicaEste trabalho apresenta o estudo da metodologia de projeto de produtos modulares denominado MFD (Modular Function ...
Bataglin, Marcelo
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