Results 81 to 90 of about 12,907,560 (338)

Integrating Design for Manufacturing and Assembly Principles in Modular Home Construction: A Comprehensive Framework for Enhanced Efficiency and Sustainability

open access: yesBuildings
The growing demand for sustainable and efficient construction practices has led to an increased interest in modular construction, with design for manufacture and assembly emerging as a pivotal approach.
Sadaf Montazeri   +3 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Modulinio projektavimo taikymo paslaugoms problematika / Problematic of service modularisation

open access: yesMokslas: Lietuvos Ateitis, 2019
Maintaining a competitive edge in today’s markets with short product life cycles and competitors quickly copying commercial success ideas is a significant challenge.
Ilona Skačkauskienė, Jurga Vestertė
doaj   +1 more source

Design of a Hybrid Modular Switch

open access: yes, 2017
Network Function Virtualization (NFV) shed new light for the design, deployment, and management of cloud networks. Many network functions such as firewalls, load balancers, and intrusion detection systems can be virtualized by servers.
Aghdai, Ashkan   +2 more
core   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

Preliminary structural design method for modular wing

open access: yesHangkong gongcheng jinzhan
Aircraft modular design can increase the types of missions and reduce costs. In the initial stage of wing modular structure design,the unclearness of wingtip deformation limits the ability to assess the contribution differences of structural stiffness ...
FAN Fulei   +3 more
doaj   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

A Monte-Carlo Approach to Lifespan Failure Performance Analysis of the Network Fabric in Modular Data Centers

open access: yes, 2017
Data centers have been evolved from a passive element of compute infrastructure to become an active, core part of any ICT solution. In particular, modular data centers (MDCs), which are a promising design approach to improve resiliency of data centers ...
Asghari, Vahid   +4 more
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

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