Results 101 to 110 of about 10,207,502 (288)

Innovative Design of a Vertical Retractable Multipurpose Support System

open access: yesDesigns
The Support System with Vertical Retractable Mechanism (SSVRS) is an advancement in telescopic technology that replaces continuous threaded or fluid-dependent interfaces with an internal stepped mechanism based on geometric mechanical interference.
Elkin I. Gutierrez-Velasquez   +2 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Freight Railway Train of Modular Type

open access: yesМеханика машин, механизмов и материалов, 2012
This paper gives theoretical substantiation for the effectiveness of replacing the traditional scheme of freight train, representing a chain of cars all successively connected to the locomotive by a modular scheme, where the rolling stock is assembled of
I.K. Alexandrov
doaj  

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

Applying modular design principles of adverse outcome pathways to experimental planning in toxicology

open access: yesEvidence-Based Toxicology
Adverse outcome pathways (AOPs) offer a modular framework that can transform experimental planning in toxicology beyond their current use in organising knowledge.
Devon A. Barnes   +2 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Método para auxiliar as escolhas das configurações e de uma arquitetura de enfoque modular para famílias de produtos [PDF]

open access: yes, 2008
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Mecânica.Esta tese é motivada pela crescente necessidade manifestada pelos consumidores por produtos diferenciados e pelo ...
Martini, José Nilton
core  

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Modular lightweight design - Opportunities and challenges in the digitized development process

open access: yes, 2019
In this paper the modular lightweight design is introduced as a solution to combine the contrary aspects of modularization and lightweight design. Therefore.
Krause, Dieter   +2 more
core   +3 more sources

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