Results 41 to 50 of about 51,985 (260)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Modular curves, the Tate-Shafarevich group and Gopakumar-Vafa invariants with discrete charges
Journal of High Energy Physics, 2022 We show that the stringy Kähler moduli space of a generic genus one curve of degree N, for N ≤ 5, is the Γ1(N) modular curve X 1(N). This implies a correspondence between the cusps of the modular curves and certain large volume limits in the stringy ...
Thorsten Schimannek
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Stability of general A-cubic functional equations in modular spaces
Revista de la Real Academia de Ciencias Exactas, Físicas y Naturales. Serie A. Matemáticas, 2017 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Eskandani, G.Z., Rassias, J.M.
openaire +3 more sources
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Modular factorization of superconformal indices
Journal of High Energy Physics, 2023 Superconformal indices of four-dimensional N $$ \mathcal{N} $$ = 1 gauge theories factorize into holomorphic blocks. We interpret this as a modular property resulting from the combined action of an SL(3, ℤ) and SL(2, ℤ) ⋉ ℤ 2 transformation.
Vishnu Jejjala +3 more
doaj +1 more source
INTEGRAL OF FUNCTION WITH VALUES IN COMPLETE MODULAR SPACE
Demonstratio Mathematica, 2002 The paper is devoted to constructing and examining integrals of functions with values in modular spaces, i.e., real vector spaces provided with a convex, symmetric nonnegative functional vanishing only at 0.
openaire +2 more sources
A Korovkin theorem in multivariate modular function spaces [PDF]
Journal of Function Spaces, 2009 In this paper a modular version of the classical Korovkin theorem in multivariate modular function spaces is obtained and applications to some multivariate discrete and integral operators, acting in Orlicz spaces, are given.
BARDARO, Carlo, MANTELLINI, Ilaria
openaire +2 more sources