Results 31 to 40 of about 10,724 (253)
Uniformly Lipschitzian mappings in modular function spaces [PDF]
Plan Andaluz de Investigación (Junta de Andalucía)
Domínguez Benavides, Tomás +2 more
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Fuzzy Isometry and Standard Modular Structures in Modular Fuzzy Metric Spaces
This paper investigates the relationship between modular metric spaces and modular fuzzy metric spaces by introducing and studying the concept of the standard modular fuzzy metric space.
Mohammed Jawad Kadhim
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Chern-Simons invariants from ensemble averages
We discuss ensemble averages of two-dimensional conformal field theories associated with an arbitrary indefinite lattice with integral quadratic form Q.
Meer Ashwinkumar +4 more
doaj +1 more source
Spaces of states of the two-dimensional $O(n)$ and Potts models
We determine the spaces of states of the two-dimensional $O(n)$ and $Q$-state Potts models with generic parameters $n,Q\in \mathbb{C}$ as representations of their known symmetry algebras.
Jesper Lykke Jacobsen, Sylvain Ribault, Hubert Saleur
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Stability of general A-cubic functional equations in modular spaces
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Eskandani, G.Z., Rassias, J.M.
openaire +3 more sources
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source

