Microphysiological Systems of Lymphatics and Immune Organs
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
The xIV-LDDMM toolkit of image-varifold based technologies for mapping 3D images and spatial-omics across scales. [PDF]
Stouffer KM +6 more
europepmc +1 more source
Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl +8 more
wiley +1 more source
Unraveling the mesoscale organization induced by network-driven processes. [PDF]
Barzon G +3 more
europepmc +1 more source
Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi +7 more
wiley +1 more source
Adaptive neuromodulation dialogues: navigating current challenges and emerging innovations in neuromodulation system development. [PDF]
Lampert F +28 more
europepmc +1 more source
Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour +11 more
wiley +1 more source
Comparative Benchmark of Sampling-Based and DRL Motion Planning Methods for Industrial Robotic Arms. [PDF]
Astorquia IF +3 more
europepmc +1 more source
Personalized learning support system for special education: a real-time feedback mechanism based on deep reinforcement learning. [PDF]
Liu H.
europepmc +1 more source
Structured generative modelling of earthquake response spectra with hierarchical latent variables in hyperbolic geometry. [PDF]
Wright A, Fayaz J.
europepmc +1 more source

