Results 91 to 100 of about 4,629,646 (278)

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

On the modular metric completion [PDF]

The purpose of this paper is to present the construction of the completion of a set equipped with a modular metric that we call the modular completion. We show for instance that any set equipped with a modular metric has a modular completion.
Olela-Otafudu, Olivier, Olela Otafudu, Olivier, Phawe, Tlotlo Odacious   +2 more
core   +1 more source

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo, Claudia Dosi, Stefano Parravicini, Riccardo Zanin, Marta Cheli, Eleonora Giacopuzzi Grigoli, Amalia Canciello, Francesca Andreetta, Riccardo Masson, Silvia Bonanno, Stefania Marcuzzo, Lorenzo Maggi   +11 more
wiley   +1 more source

Fixed point results of a-bY-F-Geraghty type contractive mapping on modular b-metric spaces [PDF]

Mathematica Moravica
In this paper, we generalize a-bY-F-Geraghty type contraction in modular b-metric spaces and prove some fixed point results that are justified by suitable examples.
Jain Shishir, Sharma Yogita, Jain Shobha, Sharma Sumit   +3 more
doaj   +1 more source

Nonio — modular automatic compiler phase selection and ordering specialization framework for modern compilers

SoftwareX, 2019
This article presents Nonio, a modular, easy-to-use, design space exploration framework focused on exploring custom combinations of compiler flags and compiler sequences. We describe the framework and discuss its use with two of the most popular compiler
Ricardo Nobre, João Bispo, Tiago Carvalho, João M.P. Cardoso   +3 more
doaj   +1 more source

Improving the Diagnostic Accuracy of Plasma Alzheimer's Disease Biomarkers With Objective and Subjective Cognitive Screening

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Blood‐based biomarkers are increasingly used to identify Alzheimer's disease (AD) pathology and may play an important role in early disease screening and participant selection for clinical trials. However, their performance across stages of cognitive impairment remains unclear. This study examined whether plasma biomarkers differ in
Maryam Abdolmaleki, Leslie S. Gaynor, Dandan Liu, Timothy J. Hohman, Katherine A. Gifford, Henrik Zetterberg, Angela L. Jefferson, Corey J. Bolton   +7 more
wiley   +1 more source

Meir-Keeler type contractions on modular metric spaces

Filomat, 2018
In this paper we introduce contraction mappings of Meir-Keeler types on modular metric spaces and investigate the existence and uniqueness of their fixed points. We give an example which demonstrates our theoretical results.
Aksoy, Ümit, Karapınar, Erdal, Erhan, İnci M., Rakočević, Vladimir   +3 more
openaire   +3 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

On Modular b-Metrics [PDF]

[EN] The notions of modular b-metric and modular b-metric space were introduced by Ege and Alaca as natural generalizations of the well-known and featured concepts of modular metric and modular metric space presented and discussed by Chistyakov.
Romaguera Bonilla, Salvador, Salvador Romaguera   +1 more
core   +1 more source