Results 51 to 60 of about 4,629,646 (278)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
FIXED POINT OF MULTIVALUED CONTRACTIONS IN ORTHOGONAL MODULAR METRIC SPACES [PDF]
Facta Universitatis, Series: Mathematics and Informatics, 2019 In this paper we generalize the notion of O−set and establish some fixedpoint theorems for ⊥ − α − ψ−contraction multifunction in the setting of orthogonalmodular metric spaces. As consequences of these results we deduce some theorems inorthogonal modular metric spaces endowed with a graph and partial order.
Hosseini, Hoda, Gordji, Majid Eshaghi
openaire +2 more sources
Modular spaces and topologies on modular spaces [PDF]
, 2023 Yüksek Lisans TeziTezimiz dört bölümden oluşmaktadır. Birinci bölümde metrik uzaylar ve modüler metrik ile ilgili genel bilgi verilerek matematikteki tarihsel gelişimi verilmiştir.
Haşimoğlu, Firdevs
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Emergence of spacetime from the algebra of total modular Hamiltonians
Journal of High Energy Physics, 2019 We study the action of the CFT total modular Hamiltonian on the CFT representation of bulk fields with spin. In the vacuum of the CFT the total modular Hamiltonian acts as a bulk Lie derivative, reducing on the RT surface to a boost perpendicular to the ...
Daniel Kabat, Gilad Lifschytz
doaj +1 more source
A Simplified Quantum Walk Model for Predicting Missing Links of Complex Networks
Entropy, 2022 Prediction of missing links is an important part of many applications, such as friends’ recommendations on social media, reduction of economic cost of protein functional modular mining, and implementation of accurate recommendations in the shopping ...
Wen Liang +4 more
doaj +1 more source
Fixed point results for generalized F-contractions in modular metric and fuzzy metric spaces [PDF]
Fixed Point Theory and Applications, 2015 AbstractThe notion of modular metric space, being a natural generalization of classical modulars over linear spaces, was recently introduced. In this paper, we introduce a generalized F-contraction in modular metric space and investigate the existence of fixed points for such contractions.
Nawab Hussain, Abdul Latif, Iram Iqbal
openaire +2 more sources