Results 81 to 90 of about 1,857 (223)
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Modular invariance and uniqueness of conformal characters
We show that the conformal characters of various rational models of W-algebras can be already uniquely determined if one merely knows the central charge and the conformal dimensions.
Bonn Univ. (Germany). Physikalisches Inst. +2 more
core
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Modular Representation Theory- Central Characters, Tensor Products, and Decomposition
Lecture notes linking central characters, blocks, projective indecomposables, and decomposition/Cartan matrices, with an emphasis on computing decomposition data via traces on p-regular classes and tensor constructions. Develops central characters and their mod-p reductions to define blocks; builds projective characters (vanishing on p-singular ...
openaire +1 more source
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Modular Representation Theory- Block Idempotents, Central Characters, and Decompositions
These notes develop a structural, computation-ready view of modular representation theory through the lens of the group algebra’s center. Beginning with class sums and the decomposition of Z(FG) into block subalgebras, they define block idempotents and central characters and show that blocks can be characterized equivalently via reduced central ...
openaire +2 more sources
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Lecture Notes- Modular Representation Theory and Brauer Characters of A_5
A focused set of notes on modular representation theory for the alternating group A₅ (|A₅| = 60). Topics include congruence conditions (mod 2, 3, 5), construction of Brauer characters from p-regular classes, and assembly/interpretation of the decomposition matrix D linking ordinary and modular characters.
openaire +2 more sources

