Results 61 to 70 of about 163,347 (232)

Multi instanton calculus on ALE spaces

open access: yes, 2004
We study SYM gauge theories living on ALE spaces. Using localization formulae we compute the prepotential (and its gravitational corrections) for SU(N) supersymmetric ${\cal N}=2, 2^*$ gauge theories on ALE spaces of the $A_n$ type.
Bellisai   +29 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Banach Contraction Principle-Type Results for Some Enriched Mappings in Modular Function Spaces

open access: yesAxioms, 2023
The idea of enriched mappings in normed spaces is relatively a newer idea. In this paper, we initiate the study of enriched mappings in modular function spaces.
Safeer Hussain Khan   +2 more
doaj   +1 more source

A note on conditional risk measures of Orlicz spaces and Orlicz-type modules

open access: yes, 2016
We consider conditional and dynamic risk measures of Orlicz spaces and study their robust representation. For this purpose, given a probability space $(\Omega,\mathcal{E},\mathbb{P})$, a sub-$\sigma$-algebra $\mathcal{F}$ of $\mathcal{E}$, and a Young ...
Orihuela, José, Zapata, José Miguel
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Fixed Points of Kannan Maps in the Variable Exponent Sequence Spaces p(·)

open access: yesMathematics, 2020
Kannan maps have inspired a branch of metric fixed point theory devoted to the extension of the classical Banach contraction principle. The study of these maps in modular vector spaces was attempted timidly and was not successful.
Afrah A. N. Abdou   +1 more
doaj   +1 more source

Modular Spaces Topology

open access: yesApplied Mathematics, 2013
In this paper, we present and discuss the topology of modular spaces using the filter base and we then characterize closed subsets as well as its regularity.
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Modular Uniform Convexity in Every Direction in Lp(·) and Its Applications

open access: yesMathematics, 2020
We prove that the Lebesgue space of variable exponent L p ( · ) ( Ω ) is modularly uniformly convex in every direction provided the exponent p is finite a.e. and different from 1 a.e.
Mostafa Bachar, Osvaldo Méndez
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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