Results 61 to 70 of about 173,441 (284)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Modular Uniform Convexity in Every Direction in Lp(·) and Its Applications
Mathematics, 2020 We prove that the Lebesgue space of variable exponent L p ( · ) ( Ω ) is modularly uniformly convex in every direction provided the exponent p is finite a.e. and different from 1 a.e.
Mostafa Bachar, Osvaldo Méndez
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
International Journal of Analysis and Applications, 2023 In this work, we investigate the generalised Hyers-Ulam stability of additive functional inequality in modular spaces with ∆2-conditions and in β-homogeneous Banach spaces.
Abderrahman Baza, Mohamed Rossafi
doaj +1 more source
Multi instanton calculus on ALE spaces
, 2004 We study SYM gauge theories living on ALE spaces. Using localization formulae we compute the prepotential (and its gravitational corrections) for SU(N) supersymmetric ${\cal N}=2, 2^*$ gauge theories on ALE spaces of the $A_n$ type.
Bellisai +29 more
core +1 more source
Applied Mathematics, 2013 In this paper, we present and discuss the topology of modular spaces using the filter base and we then characterize closed subsets as well as its regularity.
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Linear functionals on Orlicz sequence spaces without local convexity
International Journal of Mathematics and Mathematical Sciences, 1992 The general form of continuous linear functionals on an Orlicz sequence space 1ϕ (non-separable and non-locally convex in general) is obtained. It is proved that the space hϕ is an M-ideal in 1ϕ.
Marian Nowak
doaj +1 more source
Common fixed points of monotone ρ-nonexpansive semigroup in modular spaces
Fixed Point Theory and Applications, 2020 In this paper, we consider the class of monotone ρ-nonexpansive semigroups and give existence and convergence results for common fixed points. First, we prove that the set of common fixed points is nonempty in uniformly convex modular spaces and modular ...
Noureddine El Harmouchi +2 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source