Results 201 to 210 of about 59,853 (261)

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Understanding the potential of probiotics in oral cancer prevention: a short review on microbial modulation. [PDF]

Discov Oncol
Rivera C.
europepmc   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Cell-to-cell communication: from physical calling to remote emotional touching. [PDF]

Discov Nano
Banaeian Far S, Chalak Qazani MR, Imani Rad A.   +2 more
europepmc   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

A CMOS Hybrid System for Non-Invasive Hemoglobin and Oxygen Saturation Monitoring with Super Wavelength Infrared Light Emitting Diodes. [PDF]

Micromachines (Basel)
Park H, Kang S, Kim J, Lee J, Park S, Park SM.   +5 more
europepmc   +1 more source

Experimental Performance Analysis of Large-Format 304 Stainless Steel Surface Laser Matting Process. [PDF]

Materials (Basel)
Ding Q, Wang M, Wang X, Huang P, Wang Z, Ji Y.   +5 more
europepmc   +1 more source

Design and Implementation of a Multi-Mode Telemetry Transmitter. [PDF]

Sensors (Basel)
Silino F, Dell'Acqua F, Vizziello A, Biz D, Costa F, Savazzi P.   +5 more
europepmc   +1 more source

Priestia megaterium reduces hydrogen sulfide level in swine manure potentially through an assimilatory mechanism and microbiota modulation. [PDF]

Appl Microbiol Biotechnol
Kim SH, Vasquez R, Song JH, Kang DK.
europepmc   +1 more source