Results 121 to 130 of about 5,478 (167)

Pharmacologic stimulation of insulin granule acidification increases β-cell zinc content and augments β-cell-targeted drug delivery. [PDF]

J Biol Chem
Lee S, Fraser HP, Schugar RC, Xu H, Horton TM, Thomson EA, Park J, Zhang X, Annes JP.   +8 more
europepmc   +1 more source

ENPP1/CD203a-targeting heavy-chain antibody reveals cell-specific expression on human immune cells. [PDF]

Cell Mol Life Sci
Lorenz H, Menzel S, Roshchyna N, Albrecht B, Gebhardt AJ, Schneider E, Haag F, Rissiek B, Oheim R, Koch-Nolte F, Winzer R, Tolosa E.   +11 more
europepmc   +1 more source

Development of a PRAME pMHC targeted T cell engager for solid tumor therapy. [PDF]

MAbs
Skrzypczynska K, Schimert K, Stephenson H, Mah IK, Mortenson D, Boyd K, Hardman T, Novikov N, Seto E, Lu S, Yen R, Lee B, Wang M, Kang D, Huang Y, Yu X, Hung M, Ding S, Thomsen N, Oakdale NS.   +19 more
europepmc   +1 more source

Obesity enhances ovarian cancer chemotherapy efficacy through C1q-mediated tumor targeting and immune activation. [PDF]

J Nanobiotechnology
Xu S, Bie N, Su X, Zhang X, Li S, Liu H, Yong T, Chen Q, Yang X, Gan L.   +9 more
europepmc   +1 more source

Discovery and Functional Validation of EP3 Receptor Ligands with Therapeutic Potential in Cardiovascular Disease. [PDF]

Int J Mol Sci
Alonso-Fernández JR, Montoro-García S, Cruz AF, Ponce-Valencia A, Carmena-Bargueño M, Pérez-Sánchez H.   +5 more
europepmc   +1 more source

Single-cell analysis of uterine artery endothelial cells reveals cytokine-induced emergence of specific immunomodulatory subtypes: implications for preeclampsia. [PDF]

J Mol Endocrinol
Dahn RL, Lett BM, Clemente L, Austin JL, Yi FX, Boeldt DS, Stanic AK, Ong IM, Bird IM.   +8 more
europepmc   +1 more source

Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4⁺ T cells to confer protection against intestinal inflammation. [PDF]

Nat Metab
Li Q, de Oliveira Formiga R, Puchois V, Creusot L, Ahmad AH, Amouyal S, Campos-Ribeiro MA, Zhao Y, Harris DMM, Lasserre F, Ellero-Simatos S, Guillou H, Huang Z, Brot L, Hu Y, Chollet L, Danne C, Scandola C, Ledent T, Chevreux G, Argüello RJ, De Carvalho Bittencourt M, Bettinger J, D'Aveni-Piney M, Moulin D, Schreiber S, Aden K, Rolhion N, Michel ML, Wai T, Sokol H.   +30 more
europepmc   +1 more source

Single-Cell Analysis Reveals Aspirin Restores Intervertebral Disc Integrity via Ferroptosis Regulation. [PDF]

J Inflamm Res
Niu H, Qi H, Zhang P, Meng H, Liu N, Zhang D.   +5 more
europepmc   +1 more source

Meta-unstable mRNAs in activated CD8⁺ T cells are defined by interlinked AU-rich elements and m⁶A mRNA methylation. [PDF]

Nat Commun
Gameiro PA, Foskolou IP, Butt YA, Martens AAM, Kuret Hodnik K, Ruiz de Los Mozos I, Zandhuis ND, Hozjan Ž, Kot VM, Faraway R, Vermeulen M, Wolkers MC, Johnson RS, Ule J.   +13 more
europepmc   +1 more source

SC134-TCB Targeting Fucosyl-GM1, a T Cell-Engaging Antibody with Potent Antitumor Activity in Preclinical Small Cell Lung Cancer Models. [PDF]

Mol Cancer Ther
Dave F, Vaghela P, Heath B, Dunster Z, Dubinina E, Thakker D, Mann K, Chadwick J, Cane G, Kaira BG, Mohammed OJ, Choudhury R, Paston S, Parsons T, Vankemmelbeke M, Durrant L.   +15 more
europepmc   +1 more source