A lightweight two-stage convolutional (deep) neural network (CNN) based modulation format identification (MFI) scheme is proposed and demonstrated for the polarization domain multiplexing (PDM) fiber communication system with probabilistically shaped (PS)
Wenbo Zhang +6 more
doaj +1 more source
Cell-type specific potent Wnt signaling blockade by bispecific antibody. [PDF]
Cell signaling pathways are often shared between normal and diseased cells. How to achieve cell type-specific, potent inhibition of signaling pathways is a major challenge with implications for therapeutic development.
Bidlingmaier, Scott +6 more
core +2 more sources
Modulation format identification (MFI) is necessary for future elastic optical networks. We propose an MFI scheme based on the amplitude deviation analysis of the received optical communication signal.
Zhao Zhao +3 more
doaj +1 more source
Machine Learning Applications for Short Reach Optical Communication
With the rapid development of optical communication systems, more advanced techniques conventionally used in long-haul transmissions have gradually entered systems covering shorter distances below 100 km, where higher-speed connections are required in ...
Yapeng Xie +3 more
doaj +1 more source
March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity. [PDF]
In transplantation, donor dendritic cells (do-DCs) initiate the alloimmune response either by direct interaction with host T cells or by transferring intact donor MHC to host DCs.
Abdi, Reza +21 more
core +3 more sources
A Density Clustering Algorithm for Simultaneous Modulation Format Identification and OSNR Estimation
In this work, we propose a combined method to implement both modulation format identification (MFI) and optical signal-to-noise ratio (OSNR) estimation, a method based on density-based spatial clustering of applications with a noise (DBSCAN) algorithm ...
Zhao Zhao +3 more
doaj +1 more source
Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. [PDF]
In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection.
Barth, Heidi +4 more
core +2 more sources
Pathogen- and Host-Directed Antileishmanial Effects Mediated by Polyhexanide (PHMB) [PDF]
BACKGROUND:Cutaneous leishmaniasis (CL) is a neglected tropical disease caused by protozoan parasites of the genus Leishmania. CL causes enormous suffering in many countries worldwide. There is no licensed vaccine against CL, and the chemotherapy options
A Ponte-Sucre +63 more
core +4 more sources
Mesenchymal stem cell-conditioned medium reduces disease severity and immune responses in inflammatory arthritis [PDF]
We evaluated the therapeutic potential of mesenchymal stem cell-conditioned medium (CM-MSC) as an alternative to cell therapy in an antigen-induced model of arthritis (AIA). Disease severity and cartilage loss were evaluated by histopathological analysis
A Aggarwal +77 more
core +3 more sources
Primary fibroblasts from CSPα mutation carriers recapitulate hallmarks of the adult onset neuronal ceroid lipofuscinosis [PDF]
Mutations in the co- chaperone protein, CSPα, cause an autosomal dominant, adult-neuronal ceroid lipofuscinosis (AD-ANCL). The current understanding of CSPα function exclusively at the synapse fails to explain the autophagy-lysosome pathway (ALP ...
Benitez, Bruno A, Sands, Mark S
core +2 more sources

