Results 221 to 230 of about 776,397 (353)

Thermal Crosstalk in Integrated DFB Laser-EA Modulators

, 2007
Kayastha Madhusudan, Koichi Wakita, K. Baba   +2 more
openalex   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Selective oestrogen receptor modulators and Alzheimer´s disease: a real-world pharmacovigilance study. [PDF]

Eur J Clin Pharmacol
Yuste MT, Badillo E, Galecio JS, Marín P.   +3 more
europepmc   +1 more source

Silicon-organic hybrid fabrication platform for integrated circuits [PDF]

, 2012
Absil, Philippe, Alloatti, Luca, Baets, Roel, Bogaerts, Wim, Bossard, Martin, Dispenza, Massimiliano, Freude, Wolfgang, Gunter, Peter, Jazbinsek, Mojca, Komorowska, Katarzyna, Koos, Christian, Korn, Dietmar, Lauermann, Matthias, Leuthold, Juerg, Moelants, Myriam, Palmer, Robert, Pfeifle, Jörg, Schindler, Philipp C, Secchi, Alberto, Tomkos, Ioannis, Van Campenhout, Joris, Verheyen, Peter, Wehrli, Silvan, Wouters, Johan, Yu, Hui, Zakynthinos, Panagiotis   +25 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Low risk of severe COVID-19 in vaccinated people with multiple sclerosis: a nationwide Norwegian study. [PDF]

BMJ Neurol Open
Rasmussen TH, Schikora-Rustad S, Lorentzen ÅR, Tran TT, Øverås MH, Myhr KM, Wergeland S, Aarseth J, Bø L, Berge T, Høgestøl EA, Harbo HF, Tveter AT, Jørgensen KK, Cunen C, Torkildsen Ø, Holmøy T, Celius EG, Vaage JT, Nygaard GO, Lund-Johansen F, König M.   +21 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

6,7-Dihalo-Benzothiadiazines as Potent and Selective AMPA Receptor Modulators for Cognitive Enhancement and Neuroprotection. [PDF]

ACS Med Chem Lett
Li Y, Yuan H, Liang SH.
europepmc   +1 more source

Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720 [PDF]

, 2002
Maria R. Baer, Stephen L. George, Richard K. Dodge, Kieran L. O’Loughlin, Hans Minderman, Michael A. Caligiuri, John Anastasi, Bayard L. Powell, Jonathan E. Kolitz, Charles A. Schiffer, Clara D. Bloomfield, Richard A. Larson   +11 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source