Results 111 to 120 of about 461,998 (240)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Evaluation and Validation of Different Integrated Pest Management Modules for Field Pea

open access: yesInternational Journal of Bio-Resource and Stress Management
This research was carried out during rabi (November-March) 2020–21 at Agronomy Instructional Farm, S. D. Agricultural University, Sardarkrushinagar, Gujarat, India to evaluate the efficacy of seven different Integrated Pest Management (IPM) modules ...
J. V. Chauhan   +4 more
doaj   +1 more source

Measurability in modules

open access: yesArchive for Mathematical Logic, 2014
Motivated by the example of finite fields and quasi-finite fields, \textit{D. Macpherson} and \textit{C. Steinhorn} [Trans. Am. Math. Soc. 360, No. 1, 411--448 (2008; Zbl 1127.03026)] introduced a dimension/measure theory for certain classes of finite structures. This concept was developed further in [\textit{R. Elwes} and \textit{D. Macpherson}, Lond.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

modules: timcdlucasInternshipModules

open access: yes, 2014
<p>This is the modules repository at the end of my 3 month internship.
Emiel van Loon   +3 more
core   +1 more source

Modulating Modulation [PDF]

open access: yesThe Journal of General Physiology, 2000
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The homotopy categories of injective modules of derived discrete algebras [PDF]

open access: yes, 2013
Zhe H. The homotopy categories of injective modules of derived discrete algebras.
Zhe, Han
core  

Metabolite coupling analysis and metabolite-flux coupling analysis of genome-scale metabolic models

open access: yesFrontiers in Bioinformatics
BackgroundGenome-scale metabolic models (GEMs) provide detailed representations of metabolic networks. Flux Coupling Analysis (FCA) is widely used for analyzing dependencies between reaction fluxes in GEMs.ResultsWe introduce Metabolite Coupling Analysis
Mingyuan Tian, Mingyuan Tian
doaj   +1 more source

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