Results 261 to 270 of about 684,019 (318)

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke, Petra Steinacker, Steffen Halbgebauer, Patrick Oeckl, Geert Mayer, Markus Otto   +5 more
wiley   +1 more source

Nested co-expression network analysis identifies compact gene clusters in a black box. [PDF]

Bioinformatics
Dyugay IA, Poslavsky A, Lukyanov DK, Polyakov FM, Nikitin E, Klimuk E, Dakhnovets A, Syrko DS, Kotliar VV, Chudakov DM.   +9 more
europepmc   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Molecular Principles of Gating Proton Transport in the Antiporter Modules of Respiratory Complex I. [PDF]

J Am Chem Soc
Badolato S, Rossmann SC, Pereira J, Kim H, Kaila VRI.   +4 more
europepmc   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Modular living assembly of bone organoids with in situ guided vascularization. [PDF]

Bioact Mater
Ju J, Fang H, Jie J, Wu Y, Wang J, Gao Q, Zhang Y, Luo C, Zheng H, Sun J, Su J, Wang Z.   +11 more
europepmc   +1 more source

Hybrid additive manufacturing-based assembly of sacrificial isomalt scaffolds and gas exchange membranes for microfluidic artificial lung development. [PDF]

Microsyst Nanoeng
Sojan A, Fusch G, Amin S, Rochow N, Fusch C, Selvaganapathy PR.   +5 more
europepmc   +1 more source

Sex and tissue resolved co-expression networks reveal a female placental-brain axis protective against prenatal PCB exposure. [PDF]

Genome Biol
Chau KH, Neier K, Valenzuela AE, Schmidt RJ, Durbin-Johnson B, Lein PJ, Korf I, LaSalle JM.   +7 more
europepmc   +1 more source