Results 31 to 40 of about 964 (198)

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum   +5 more
wiley   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister   +14 more
wiley   +1 more source

Flexible Polypyrrole‐Based pH Sensors via Oxidative Chemical Vapor Deposition

open access: yesAdvanced Healthcare Materials, EarlyView.
Oxidative chemical vapor deposition (oCVD) of polypyrrole (PPy) thin films yields flexible, electrically conductive, and biocompatible pH sensors for monitoring on‐skin biological events. The highly sensitive, oCVD PPy skin‐conformal sensors enable real‐time, spatially resolved sensing of dynamic pH changes within physiologically relevant ranges (4–9 ...
Adrivit Mukherjee   +15 more
wiley   +1 more source

Thermomechanics of Picoliter Liquids Encapsulated in Metal Microarchitectures

open access: yesAdvanced Materials, EarlyView.
Picoliter‐scale water is encapsulated inside hollow copper microcylinders through a single‐step localized electrodeposition process. Mechanical testing at room and cryogenic temperatures reveals that incompressible liquid and load‐bearing microscale ice enhance the strength and deformation behavior of the composite structure.
Sung‐Gyu Kang   +15 more
wiley   +1 more source

From Fiber Architecture to Functional Attachment: A Clinically Relevant, Mechanically Tunable Cardiac Patch

open access: yesAdvanced Materials, EarlyView.
A personalizable platform featuring a multi‐zonal cardiac patch design at clinical scale enables precise customization of fiber architecture at micro‐ and macroscale via melt electrowriting. Distinct scaffold zones support cell alignment with mechanical force transfer and epicardial attachment.
Johannes Braig   +31 more
wiley   +1 more source

Generative Models for Crystalline Materials

open access: yesAdvanced Materials, EarlyView.
Generative machine learning models are increasingly used in crystalline materials design. This review outlines major generative approaches and assesses their strengths and limitations. It also examines how generative models can be adapted to practical applications, discusses key experimental considerations for evaluating generated structures, and ...
Houssam Metni   +15 more
wiley   +1 more source

Adaptation of Moreau–Yosida regularization to the modulus of convexity

open access: yesJournal of Mathematical Analysis and Applications
We study a generalization of Moreau-Yosida regularization that is adapted to the geometry of Banach spaces where the dual space is uniformly convex with modulus of convexity of power type. Important properties for regularized convex functions are given, in particular strong monotonicity of the subdifferential of their convex conjugate and Hölder ...
Markus Penz, Andre Laestadius
openaire   +3 more sources

Droplet Electricity Generators With Maximized Energy Collection Zone Enabled by Aloe‐Inspired Midrib and Cuticle

open access: yesAdvanced Materials, EarlyView.
An Aloe‐pinspired droplet electricity generator (A‐DEG) overcomes the limited energy collection zone of conventional DEGs by guiding impact droplets through a channeling midrib and artificial cuticle. The channeling midrib induces uni‐directional droplet spreading, while the artificial cuticle on the midrib further reinforces this behavior through its ...
Gibeom Lee   +8 more
wiley   +1 more source

Modulus of Convexity, the Coeffcient R(1, X), and Normal Structure in Banach Spaces [PDF]

open access: yesAbstract and Applied Analysis, 2008
Let δX(ϵ) and R(1, X) be the modulus of convexity and the Domínguez‐Benavides coefficient, respectively. According to these two geometric parameters, we obtain a sufficient condition for normal structure, that is, a Banach space X has normal structure if 2δX(1 + ϵ) > max{(R(1, x) − 1)ϵ, 1 − (1 − ϵ/R(1, X) − 1)} for some ϵ ∈ [0, 1] which ...
Jiao, Hongwei   +2 more
openaire   +4 more sources

BLOC: Buildable and Linkable Organ on a Chip

open access: yesAdvanced Materials Technologies, EarlyView.
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura   +7 more
wiley   +1 more source

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