Results 141 to 150 of about 361,214 (268)

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Antidepressant-Like Effect of an Immediate-Release Formulation of <i>Mallotus oppositifolius</i> in Mice. [PDF]

Scientifica (Cairo)
Ibrahim ZA, Adi-Dako O, Adutwum-Ofosu KK, Amoateng P, Appiah F, Koomson AE, Adongo DW, Kwapong AA, Kukuia KKE.   +8 more
europepmc   +1 more source

Multi‐Soliton Microcombs Enable Ultrafast Nanometric‐Precision Ranging and Photon‐Level Detection

Advanced Science, EarlyView.
Our work first demonstrates dual‐multi‐soliton ranging and confirms its multifunctional capability. The method achieves ultrafast and nanometric‐precision measurement. For practical applications, we further extend the multi‐soliton states to photon‐level ranging.
Jiawen Zhi, Xiaoyang Guo, Xusheng Yang, Brent E. Little, Sai T. Chu, Chenggang Shao, Mengyu Wang, Yan Liang, Peng Xie, Weiqiang Wang, Hanzhong Wu   +10 more
wiley   +1 more source

<i>DUX4</i> reduction and muscle function improvement by subcutaneous delivery of gapmer antisense oligonucleotides. [PDF]

Mol Ther Nucleic Acids
Zhang A, Lim KRQ, Chen Z, Yokota T, Chen YW.   +4 more
europepmc   +1 more source

Professors Moe and Aanonsen Named to Endowed Chairs [PDF]

, 2010
Macalester College
core   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

Massive Ovarian Edema Successfully Treated Through Accurate Preoperative Diagnosis and Laparoscopic Conservative Surgery. [PDF]

Cureus
Yagi M, Fukuda T, Wada T, Yamauchi M, Sumi T.   +4 more
europepmc   +1 more source

Hydrogen‐Bonding Networks Enabled by Trace Water for Morphological Design in Ternary Organic Solar Cells

Advanced Science, EarlyView.
Trace water transforms from an impurity to a design handle for ternary organic solar cells. During solvent evaporation, minimal amounts organize transient hydrogen‐bonding networks that steer component migration and set the morphology. The mechanism enables reproducible morphology locking and identifies a practical co‐solvent threshold near H2O:CF = 0 ...
Yue Ren, Ming‐Yue Sui, Yun Geng, Rui‐Cheng Qin, Ming‐Yang Li, Guang‐Yan Sun, Xin Xu   +6 more
wiley   +1 more source

A therapeutic antisense oligonucleotide encompassing 2'-<i>O</i>-methoxyethyl modification triggers unique perturbation of the transcriptome. [PDF]

NAR Mol Med
Ottesen EW, Murzyn WA, Kaas RL, Bertrand KJ, Payne JL, Singh RN.   +5 more
europepmc   +1 more source

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source