A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source
One-Step Separation of Propylene From Ternary C<sub>3</sub> Mixtures in Amino Acid Functionalized Metal-Organic Frameworks. [PDF]
Wang G +9 more
europepmc +1 more source
Neuromorphic Devices and Computing for Sensing, Memory, and Control
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
Bridging bioceramics and advanced 2D/porous materials: a review of hydroxyapatite/metal-organic framework and hydroxyapatite/MXene composites. [PDF]
Mobarak MB +5 more
europepmc +1 more source
Immunoregulatory strategies of MOF-based nanodrug delivery systems: Advances in cancer therapy applications and future perspectives. [PDF]
Wang L, Li F, Zhao Z, Zhao M, Luo L.
europepmc +1 more source
Expansion of the Chemical Space in UiO-Type Metal-Organic Frameworks via the Ugi Four-Component Reaction for Tuned Pore Accessibility. [PDF]
Vega EU +8 more
europepmc +1 more source
Applications and future development of solid-state nuclear magnetic resonance for investigating metal-organic frameworks. [PDF]
Chen S +4 more
europepmc +1 more source
Oriented synthesis of a cationic metal-organic framework with Al<sub>24</sub> units for effective Cr(vi) removal. [PDF]
Xiao Y +7 more
europepmc +1 more source

