Results 21 to 30 of about 101 (100)
Avoiding pitfalls when modelling ligands in macromolecular crystallography
Flawed protein–ligand X‐ray structures can misdirect drug discovery based on PDB‐deposited models. This review uses publicly available PDB examples to highlight potential pitfalls, from absent ligands to incorrect chemistry, and presents a practical validation approach to improve model reliability.The determination of protein–ligand complex structures ...
Oliver S. Smart +4 more
wiley +1 more source
Advancing AI, Virtue Enhancement, and the Need for Niebuhrian Virtues of Moral Vigilance
ABSTRACT This paper considers the possibility of AI being employed to improve moral character from the perspective of an account of virtues that is psychologically realistic (the HEIS model). It is informed by a Christian agapeic ethic oriented toward goods of creaturely well‐being that ground right action.
Gregory R. Peterson
wiley +1 more source
Home Is Where the Hope Is: Indicators of Hope in a Rural Community
ABSTRACT Sociologists have long used a deficit view in their work. However, some sociologists have recently turned to positive emotions, such as joy and hope, to provide a more complete view of marginalized and other populations. Largely, rural sociologists have not made the turn toward positive emotions.
Elizabeth A. Bennett
wiley +1 more source
Smart Sensing Systems For Agricultural Plant Health Monitoring: Current State and Prospects
Smart plant sensing technologies are critically evaluated across contact and non‐contact modalities, fabrication strategies, and diagnostic capabilities. Key deployment challenges and future research directions are identified, revealing pathways toward scalable, field‐ready systems that enable reliable, real‐time plant health monitoring and accelerate ...
Frank Efe Erukainure +1 more
wiley +1 more source
Is Blood Thicker Than Water? The Influence of Kin Within a Bull Shark Social Network
This study investigates how kinship (“kinfluence”) shapes social structure in an aggregation of adult bull sharks in Fiji by integrating genomic relatedness, pedigree reconstruction, and detailed behavioral data. It reveals that while genetic relatedness has a small but significant influence on social behavior, especially among males, kin‐category ...
Natasha D. Marosi +4 more
wiley +1 more source
Abstract Temporal changes in seismicity rates can be conceptually understood as a response and consequence of stress changes. Dieterich (1994, https://doi.org/10.1029/93JB02581) formalized this relationship using empirically derived rate‐and‐state friction laws, and Heimisson and Segall (2018, https://doi.org/10.1029/2018JB015656) later generalized the
Y. Jiang, D. T. Trugman, P. J. González
wiley +1 more source
Deciphering unusually large modulations in two related organic hydroxy channel structures
Two related organic hydroxy‐channel compounds are shown to have unusually large structural modulations.The incommensurately modulated structures of two related organic hydroxy‐channel compounds [(R)‐1‐(1,3‐dihydroxypropan‐2‐yl)‐3‐(octan‐2‐yl)urea, 1; 1‐(1,3‐dihydroxypropan‐2‐yl)‐3‐octylurea, 2] have been determined and compared to the structure of a ...
Arie van der Lee +8 more
wiley +1 more source
WE KEEP US SAFE: De‐escalation, Working Time, and Abolitionist Praxis at The Sanctuary
ABSTRACT This essay explores “de‐escalation,” the embodied practice of intervening in interpersonal conflict and crisis without resorting to police or carceral tactics. Drawing on eighteen months of ethnographic research at The Sanctuary, a non‐profit organization in Philadelphia that provides free social services, clothing, and food to vulnerable ...
JAKE NUSSBAUM
wiley +1 more source
Description of the rate‐limiting hydrogen tunneling mechanism for plant 9‐ and 13‐lipoxygenases
Abstract Soybean lipoxygenase (GmLOX1), a plant 13‐LOX, has long been considered a model protein for non‐trivial, quantum hydrogen tunneling in enzyme catalysis. Hydrogen tunneling mechanisms have also been confirmed for LOXs across mammalian, fungal, and bacterial kingdoms.
Alex Kockler +7 more
wiley +1 more source

