Results 41 to 50 of about 3,110,304 (313)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cone beam CT imaging of the mandibular third molar: a position paper prepared by the European Academy of DentoMaxilloFacial Radiology (EADMFR).

Dento maxillo facial radiology, 2019
OBJECTIVES Lack of evidence on the use of CBCT for management of mandibular third molars in Radiation Protection guideline no. 172 of the European Commission made the European Academy of DentoMaxilloFacial Radiology (EADMFR) decide to update the ...
L. H. Matzen, E. Berkhout
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Co-relation of variables as determined from panoramic radiograph and evaluating their significance in eruption of permanent mandibular third molar

Journal of Indian Academy of Oral Medicine and Radiology, 2008
Purpose of the Study: Purpose of the study is to investigate whether the variables associated with the permanent mandibular third molar (PMM3) and arch dimensions could be co-related and significantly differentiated between a fully erupted and mesially ...
Kushal Amin, K Vasavi, Sonal Vahanwala, C D Nayak, S S Pagare, S S Ramdev   +5 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Evaluatıon Of Lower Thırd Molars From An Orthodontıc Poınt Of Vıew

Turkish Journal of Orthodontics, 1996
In this article, the lower third molar teeth is evaluated under the headings: the development of lower third molars, space preparation in the dental arch before lower third molar eruption, causes of lower third molar impaction, prediction methods of ...
Aslı Ender Telli
doaj   +1 more source

Grading of Extraction and Its Relationship with Post-operative Pain and Trismus, along with Proposed Grading for Trismus [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Extraction of mandibular third molars are somewhat a matter of interest because of its malpositioning , curved roots, proximity to vital structures due to this the procedure is often associated with post operative complications like pain ...
Sachin Pathak, Shirin Vashisth, Saurabh Mishra, Surendra Pratap Singh, Shalini Sharma   +4 more
doaj   +1 more source

Immediate or delayed retrieval of the displaced third molar: A review

Journal of Clinical and Experimental Dentistry, 2019
Background The displacement of a third molar is a rare occurrence, but it could lead to serious and/or life threatening complication. Aim of this review is to understand the most correlated causes of displacement and the possible solutions proposed in ...
D. Di Nardo, G. Mazzucchi, M. Lollobrigida, C. Passariello, R. Guarnieri, M. Galli, A. De Biase, L. Testarelli   +7 more
semanticscholar   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source