Results 101 to 110 of about 186,176 (261)

Comparison of Jones jig molar distalization appliance with extraoral traction

open access: yes, 2000
In this study, 20 patients were evaluated, Ten were treated with intraoral distalization followed by fixed appliance therapy, and 10 were treated with extra oral traction followed by fixed appliance therapy.
Haydar, S, Uner, O
core   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

open access: yesAdvanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao   +12 more
wiley   +1 more source

Reliable molar distalizer: A review

open access: yesJournal of Advanced Clinical & Research Insights, 2015
Current orthodontic philosophies have been oriented toward various conservative treatment methods to eliminate extractions and also try to avoid the demand for patient compliance. The distalization of molars creates additional space within the alveolar arch, and it is of important value for the cases with minimal arch length discrepancy and Angle’s ...
P. Vasanthan   +3 more
openaire   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim   +12 more
wiley   +1 more source

Noncompliance screw supported maxillary molar distalization in a parallel manner

open access: yes, 2010
Objective: Intraoral noncompliance upper molar distalization techniques have gained in popularity and have subsequently found to be successful in Class II correction. The aim of the present study was to introduce a screw supported intraoral distalization
Bicakci, Ali Altug   +5 more
core   +1 more source

UNILATERAL DISTALIZATION OF MAXILLARY MOLAR BY PENDULUM APPLIANCE

open access: yes, 2006
Pendulum appliance is one of intraoral appliances to distalize molars for correction of class II molar relationship or space gaining in the maxillary arch. Its major advantages are: no need to depend on patient compliance; ease of fabrication; and better
Maria Purbiati, Safra Mauna
core   +2 more sources

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen   +11 more
wiley   +1 more source

Maxillary molar distalization by Pendex appliance

open access: yes, 2005
AIM: This was study to show the possibilities, indications and limitations of Pendex appliance using for upper molar distalization in mixed dentition.
F. Santoro, U. Garagiola, V. Ghiglione
core  

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

open access: yesAdvanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang   +9 more
wiley   +1 more source

Characterization of Full‐Length Antibody Complexes Through HDX‐Mass Spectrometry Coupled With NMR Spectroscopy: New Insight Into Avelumab/PD‐L1 Interaction

open access: yesAngewandte Chemie, EarlyView.
Combining HDX‐MS and NMR enables the mapping of epitopes and paratopes in full‐length antibody complexes, revealing transient interactions and potential artifacts. ABSTRACT Recombinant biomacromolecules have significantly transformed pharmaceuticals, in particular monoclonal antibodies (mAbs) that target key areas in oncology, immunology, inflammation,
Francesca Sacco   +13 more
wiley   +2 more sources

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