Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
¿“La última oportunidad” para África? Reflexiones sobre la Comisión para África y los informes del Proyecto Milenio [PDF]
, 2005 Este breve artículo pretende explorar la realidad que se esconde tras estas propuestas. Haremos hincapié en el proceso de elaboración de los informes respectivos (es decir, las circunstancias bajo las cuales se elaboraron los informes) así como en el ...
Mold, Andrew
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Electro-optical device for monitoring wire size [PDF]
, 1973 Device recognizes variations in wire size and is being used during computer memory-plane fabrication. Decrease in wire diameter, due to stretching, permits removal of wire from memory-plant mold.
Burcher, E. E., Kelly, W. L., IV
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Editorial: From Traditional to Modern: Progress of Molds and Yeasts in Fermented-Food Production [PDF]
, 2022 Wanping Chen +5 more
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Analisis Desain Mold Compression Molding untuk Komposit Peredam Suara Diameter Dua Inci
Jurnal Mekanik TerapanLimbah produk berbahan dasar karet sintetik dan polyester sangat sulit diurai secara alami sehingga dapat mencemari lingkungan. Solusi untuk menekan jumlah limbah tersebut yaitu mendaur ulang untuk dibentuk kembali menjadi produk lain contohnya sebagai ...
Muhammad Rivaldi Syahdian +1 more
doaj +1 more source
Vacuum forming of thermoplastic sheet results in low-cost investment casting patterns [PDF]
, 1964 Vacuum forming of a sheet of thermoplastic material around a mandrel conforming to the shape of the finished object provides a pattern for an investment mold.
Clarke, A. E., Jr.
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source